Denham Harman

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Denham Harman (born February 14, 1916 in San Francisco , California - † November 25, 2014 in Omaha , Nebraska ) was an American biogerontologist and professor at the University of Nebraska Medical Center in Omaha. Harman is considered the father of the free radical theory .

CV and work

Harman studied chemistry at the University of California, Berkeley . There he received his Bachelor of Science and in 1943 Ph.D. In the meantime he worked for six years in the field of organic chemistry at Shell Oil . He then studied at Stanford Medicine , where he in 1954 his MD got. In 1958 he got a call to the University of Nebraska Medical Center.

In 1954 he developed his theory of free radicals at the Faculty of Medical Physics in Berkeley , which he published in 1956.

The American Aging Association (AGE), co-founded by Harman in 1970 , has presented the Denham Harman Research Award since 1978 . He is also a co-founder of the International Association of Biomedical Gerontology .

Harman had four children with his wife, Helen. He has been nominated for the Nobel Prize in Physiology or Medicine several times .

Literature (selection)

  • D. Harman: Origin and evolution of the free radical theory of aging: a brief personal history, 1954-2009. In: Biogerontology [electronic publication before print], 2009 PMID 19466577
  • D. Harman: Alzheimer's Disease Pathogenesis: Role of Aging. In: Ann NY Acad Sci 1067, 2006, pp. 454-460. PMID 16804026 (Review)
  • D. Harman: Free radical theory of aging: an update: increasing the functional life span. In: Ann NY Acad Sci 1067, 2006, pp. 10-21. PMID 16803965 (Review)
  • D. Harman: The Free Radical Theory of Aging. In: Antioxid Redox Signal 5, 2003, pp. 557-561. PMID 14580310 (Review)
  • D. Harman: Aging: overview. In: Ann NY Acad Sci 928, 2001, pp. 1-21. PMID 11795501 (Review)
  • D. Harman: Free Radical Theory of Aging. In: Mutat Res 275, 1992, pp. 257-266. PMID 1383768 (Review)
  • D. Harman: The biological clock: the mitochondria? In: J Am Geriatr Soc 20, 1972, pp. 145-157. PMID 501663
  • D. Harman: Secondary amyloidosis and antioxidants. In: The Lancet 8194, 1980, p. 593. PMID 6106771
  • D. Harman: Mutation, Cancer, and Aging. In: The Lancet 7170, pp. 200-201. PMID 13711615

Individual evidence

  1. ↑ Denham Harman (February 14, 1916)
  2. ^ Doctor Behind 'Free Radical' Aging Theory Dies
  3. ↑ K. Kitani and GO Ivy: “I thought, thought, thought for four months in vain and suddenly the idea came” - an interview with Denham and Helen Harman mitochondrial dysfunction and aging. In: Biogerontology 4, 2003, pp. 401-412. doi : 10.1023 / B: BGEN.0000006561.15498.68
  4. ^ D. Harman: Aging: a theory based on free radical and radiation chemistry. In: J Gerontol 11, 1956, pp. 298-300. PMID 13332224
  5. ↑ Denham Harman “Harman Research Award” ( Memento of the original from December 26, 2008 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. Retrieved December 20, 2009  @1@ 2Template: Webachiv / IABot / www.americanaging.org
  6. ↑ BOARD OF DIRECTORS (2009–2010) ( Memento of the original from November 28, 2007 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. Retrieved December 20, 2009  @1@ 2Template: Webachiv / IABot / www.americanaging.org
  7. ^ M. Cheung: Finding The Fountain Of Youth. In: CBSnews June 17, 2003

Web links

personal data
SURNAME Harman, Denham
BRIEF DESCRIPTION American gerontologist
DATE OF BIRTH February 14, 1916
PLACE OF BIRTH San Francisco , California
DATE OF DEATH November 25, 2014
Place of death Omaha , Nebraska