Epithelial cell
As epithelioid cells are mesenchymal designated origin, their appearance to that of epithelial cells is similar. Their cell membranes are closely interlinked with one another. Epithelial cells in the real sense are descendants of the mononuclear phagocytosis system . Under the influence of T helper cells , they develop through differentiation from macrophages or histiocytes .
The cells are 20–40 µm in size, the nucleus is shaped like the sole of the shoe and is euchromatic, and the cytoplasm is pale and indistinct. Epithelial cells secrete various enzymes , but can only phagocytize to a limited extent . In granulomatous inflammations such as sarcoid or tuberculosis, they appear as an important cell type in the granulomas . The epithelial cells enclose the center of the granuloma so that pathogens or noxae are separated from healthy tissue ( wall formation ). The pathogens' enzymes and toxic metabolic products are largely kept local.
Individual evidence
- ↑ a b c pathologie-online.de, Inflammation II , accessed on December 5, 2012.
literature
- M. Reinhard et al: On the histochemistry of the epithelial cells in glomus tumors. In: Archives for Dermatological Research . 242/1972, pp. 165-175.
- MJ Visser et al .: Cells derived from omental fat tissue and used for seeding vascular prostheses are not endothelial in origin. A study on the origin of epitheloid cells derived from omentum. In: Journal of Vascular Surgery . 13/1991, pp. 373-381.
- Y. Latron et al .: Characterization of epitheloid cells from human omentum: comparison with endothelial cells from umbilical veins. In: Thromb Haemost . 66/1991, pp. 361-367. PMID 1746009