In 1996, Aufdenblatten won the Trofeo Topolino . In December of the same year she started to compete in FIS races , from January 1998 onwards she played in the European Cup . She first attracted attention in March 1999 when she was third in the downhill at the Swiss championships. At the Junior World Championships 2000 she won the downhill gold medal and the silver medal in combination. These results enabled Aufdenblatten on March 11, 2000 in Sestriere, the first use in the World Cup , but they could not classify. At the 2001 Junior World Championships, he won two further medals, gold in giant slalom and silver in combination. The Swiss Sports Aid Foundation recognized Aufdenblatten as Young Athlete of the Year 2001. In the same year she graduated from sports secondary school in Engelberg with the Matura .
On March 11, 2001, Aufdenblatten took 20th place in the giant slalom in Åre and thus got her first World Cup points. After she had won two European Cup races at the beginning of the 2001/02 season, she achieved her first top 5 result in Åre at the end of January 2002. When she finished third in the World Cup downhill run in Haus im Ennstal on January 31, 2004 , the breakthrough to the top of the world seemed imminent. Aufdenblatten was considered a great talent, but never quite met expectations in the following years. In the World Cup she was among the top ten more than 30 times, with one exception in January 2006 (departure in Bad Kleinkirchheim ), however, a podium was not achieved. In four participations in world championships she did not get beyond a 14th place, at the Olympic Games a 12th place was her best result.
On December 20, 2009, Aufdenblatten was able to win the only World Cup race of their career, a Super-G in Val-d'Isère . A month later, she fell in the first run of the giant slalom in Cortina d'Ampezzo and suffered a cruciate ligament rupture and a meniscus injury in her right knee, which is why she had to end the season early in the run-up to the 2010 Winter Olympics .
Four years later, a few days after achieving a diploma in Super-G at the 2014 Olympic Winter Games , Fränzi Aufdenblatten announced her resignation. Her last World Cup race, the downhill run at the season finale on Lenzerheide (March 12, 2014), she finished third on a podium.
In 2018, Aufdenblatten took part in the “Ski Tour of Life”, the Haute Route from Chamonix to Verbier , with her former teammate Dominique Gisin , among others . SRF 1 documented the ski tour in a three-part series.