Homotetramer

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A homotetrameric complex, β-glucuronidase (a glycosidase ). Each subunit has the same amino acid sequence .

A homotetramer is a protein complex that consists of four identical protein subunits , which are connected but not covalent . A heterotetramer , on the other hand, is a protein complex with four subunits in which at least one differs from the other subunits. Both are tetramers .

Examples of homotetramers would be enzymes such as β-glucuronidase ( see picture ); Export factors such as SecB in Escherichia coli and magnesium ion transporters such as CorA.

Individual evidence

  1. ^ GO term: protein homotetramerization . YeastGenome. Archived from the original on September 27, 2011. Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. Retrieved May 14, 2011. @1@ 2Template: Webachiv / IABot / www.yeastgenome.org
  2. ^ GO term: protein heterotetramerization . YeastGenome. Archived from the original on September 27, 2011. Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. Retrieved May 14, 2011. @1@ 2Template: Webachiv / IABot / www.yeastgenome.org
  3. ↑ M Watanabe, Blobel, G: Cytosolic factor purified from Escherichia coli is necessary and sufficient for the export of a preprotein and is a homotetramer of SecB. . In: Proceedings of the National Academy of Sciences . 86, No. 8, 1989 Apr, pp. 2728-32. doi : 10.1073 / pnas.86.8.2728 . PMID 2649892 . PMC 286991 (free full text).
  4. Jump up ↑ MA Warren, Kucharski, LM, Veenstra, A., Shi, L., Grulich, PF, Maguire, ME: The CorA Mg2 + Transporter Is a Homotetramer . In: Journal of Bacteriology . 186, No. 14, July 1, 2004, pp. 4605-4612. doi : 10.1128 / JB.186.14.4605-4612.2004 . PMID 15231793 . PMC 438605 (free full text).