Intravital microscopy

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Intravital microscopy (intra vital = in life) describes microscopy on living organisms, often animals. The microscopic method used is not critical. It can be, for example, normal bright field light microscopy , fluorescence microscopy or also multiphoton microscopy . Intravital microscopy is performed to study facts that cannot be examined on fixed (dead) objects or isolated cells or tissues, for example the reaction of organs to certain stimuli or chemicals.

According to Sumen, intravital microscopy was first performed by Rudolf Wagner (1839) and Julius Friedrich Cohnheim (1889).

Individual evidence

  1. ^ Sumen C, Mempel TR, Mazo IB, by Andrian UH: Intravital microscopy: visualizing immunity in context . In: Immunity . 21, No. 3, September 2004, pp. 315-29. doi : 10.1016 / j.immuni.2004.08.006 . PMID 15357943 .
  2. ^ R. Wagner, Explanatory tables on physiology and development history, Leopold Voss, Leipzig (1839).
  3. ^ J. Cohnheim, Lectures on General Pathology: A Handbook for Practitioners and Students, The New Sydenham Society, London (1889).