Janssen Pharmaceutica
| Janssen Pharmaceutica
|
|
|---|---|
 |
|
| legal form | NV |
| founding | 1953 |
| Seat | Beerse , Belgium |
| Number of employees | 3,700 |
| Branch | pharmacy |
| Website | www.janssen.com |
Janssen Pharmaceutica NV is a Belgian pharmaceutical company based in Beerse .
General
Janssen Pharmaceutica N.V. was founded in 1953 by Paul Janssen (1926–2003) and is part of the American corporation Johnson & Johnson . The original purpose of the company was exclusively pharmaceutical research.
In 1961 Janssen Pharmaceutica became the pharmaceutical division of Johnson & Johnson (one of three sectors alongside Medical Devices & Diagnostics, Consumer) after Paul Janssen wanted to devote himself more to research again and initially offered his company for sale in Europe in vain. To this day, Janssen Pharmaceutica hosts the worldwide research and development of new drugs for Johnson & Johnson (Johnson & Johnson Pharmaceutical Research Development (JJPRD)), e.g. B. in the field of neurology , anesthesia , analgesia , allergology , cancer, etc. The German branch (founded in 1959) operates under Janssen-Cilag GmbH in Neuss .
In 1985 Janssen Pharmaceutica became the first western pharmaceutical company to set up a pharmaceutical factory in the PRC . The first factory was built and managed by Joos Horsten in Hanzhong. A second and larger factory followed in Xi'an .
In 2007 Janssen Pharmaceutica was named Belgium's most attractive employer for the third time. This survey has been carried out by Randstad in Belgium since 2001.
Drugs from Janssen Pharmaceutica
| R code | Surname | Brand name | Synthesized | Marketed |
|---|---|---|---|---|
| R5 | Ambucetamide | Neomeritine | 1953 | 1955 |
| R79 | Isopropamide iodide | Priamide-Janssen | 1954 | 1955 |
| R253 | Diisopromine | Bilagol | 1955 | 1956 |
| R516 | Cinnarizine | Stugeron | 1955 | 1958 |
| R875 | Dextromoramide | Palfium | 1955 | 1957 |
| R1132 | Diphenoxylate | Reasec | 1956 | 1960 |
| R1625 | Haloperidol | Haldol | 1958 | 1959 |
| R2498 | Trifluperidol | Triperidol | 1959 | 1961 |
| R3345 | Pipamperon | Dipiperone | 1960 | 1961 |
| R3365 | Piritramide | Dipidolor | 1960 | 1967 |
| R4263 | Fentanyl | Fentanyl | 1960 | 1963 |
| R4584 | Benperidol | Glianimon | 1961 | 1965 |
| R4749 | Droperidol | Dehydrobenzperidol | 1961 | 1963 |
| R4845 | Bezitramide | Burgodin | 1961 | 1971 |
| R6218 | Flus pirils | Imap | 1963 | 1971 |
| R6238 | Pimozide | Orap | 1963 | 1970 |
| R7904 | Lidoflazine | Clinium | 1964 | 1969 |
| R11333 | Bromperidol | Impromen | 1966 | 1981 |
| R12564 | Levamisole | Ergamisole | 1966 | 1969 |
| R13672 | Haloperidol decanoate | Haldol decanoas | 1967 | 1981 |
| R14889 | Miconazole | Daktarin | 1967 | 1971 |
| R14950 | Flunarizine | Sibelium | 1967 | 1977 |
| R15889 | Lorcainide | Remivox | 1968 | 1983 |
| R16341 | Penfluridol | Semap | 1968 | 1973 |
| R16470 | Dexetimide | Tremblex | 1968 | 1972 |
| R16659 | Etomidate | Hypnomidate | 1964 | 1977 |
| R17635 | Mebendazole | Vermox | 1968 | 1972 |
| R18553 | Loperamide | Imodium | 1969 | 1973 |
| R33800 | Sufentanil | Sufenta | 1974 | 1979 |
| R33812 | Domperidone | Motilium | 1974 | 1978 |
| R35443 | Oxatomide | Ink set | 1975 | 1981 |
| R39209 | Alfentanil | Rapifen | 1976 | 1983 |
| R41400 | Ketoconazole | Nizoral | 1976 | 1981 |
| R43512 | Astemizole | Hismanal | 1977 | 1983 |
| R46541 | Bromperidol | Impromen | 1978 | 1984 |
| R49945 | Ketanserin | Sufrexal | 1980 | 1987 |
| R50547 | Levocabastine | Livostin | 1979 | 1989 |
| R51211 | Itraconazole | Sporanox | 1980 | 1986 |
| R51619 | Cisapride | Prepulsid | 1980 | 1989 |
| R64766 | Risperidone | Risperdal | 1984 | 1993 |
| R. | Paliperidone | Invega | 2007 |
Janssen Pharmaceutica has brought about 70 new substances to market over the years. The most famous among them are:
| Trade name | Non-proprietary name | indication |
|---|---|---|
| Imodium | Loperamide | Motility inhibitors |
| Motilium | Domperidone | Antiemetic |
| Reminyl | Galantamine | Anti-dementia |
| Daktarin | Miconazole | Antifungal agent |
| Nizoral | Ketoconazole | Antifungal agent |
| Vermox | Mebendazole | Anthelmintic |
| Risperdal | Risperidone | Atypical neuroleptic |
| Durogesic | Fentanyl | Opioid - analgesic |
Five Janssen drugs are on the World Health Organization's Essential Medicines List :
- Haldol ( haloperidol )
- Ergamisole ( Levamisole )
- Daktarin ( Miconazole )
- Vermox ( mebendazole )
- Nizoral ( ketoconazole ) (WHO listed since 2005)
- Risperdal ( Risperidon )
Controversy
In 2012, an Arkansas court sentenced Janssen's parent company, Johnson & Johnson, to a fine of US $ 1.2 billion. The group had been accused of having played down risks and withholding risks in the marketing of its neuroleptic Risperdal . There was evidence of an increased risk of heart attack in older people who were given Risperdal. Janssen had previously been fined $ 327 million and $ 258 million in similar rulings in South Carolina and Louisiana. The company in Texas had also agreed on a settlement of 158 million US dollars.
Web links
Individual evidence
- ↑ a b Facts & Figures , Janssen website, accessed on August 14, 2017
- ^ The Janssen Company, Janssen website, accessed August 14, 2017
- ↑ Katie Thomas: Drug Giant Is Fined $ 1.2 Billion in Risperdal Case . In: The New York Times . April 11, 2012, ISSN 0362-4331 ( nytimes.com [accessed March 27, 2019]).