Matthias Preusser

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Matthias Preusser

Matthias Preusser (born October 29, 1976 in Mödling ) is an Austrian oncologist and university professor for internal oncology, as well as head of the clinical department for oncology at the Medical University of Vienna . He is known for his work on neuro-oncology , molecular therapy targets, biomarkers, and cancer immunotherapy.

Life

Matthias Preusser studied medicine at the Medical Faculty of the University of Vienna , received his doctorate in 2003 and is a specialist in internal medicine , hematology and oncology. In 2009 he completed his habilitation in experimental oncology (Thesis: Analysis of Biomarkers in Brain Tumors ) and in 2016 in Internal Medicine (Thesis: Personalized therapy of cancer ). Preusser is the coordinator of the brain tumor unit of the Comprehensive Cancer Center - Central Nervous System (CCC-CNS). From 2009 onwards, he spent time abroad at the German Cancer Research Center in Heidelberg and at the Memorial Sloan-Kettering Cancer Center , New York. On October 1, 2018, Preusser was appointed University Professor of Internal Oncology and, on November 1, 2018, Head of the Clinical Department of Oncology at the Medical University of Vienna. In September 2019 Preusser was elected President of the European Association of Neuro-Oncology (EANO) 2021/22.

Scientific contribution

Preusser's scientific work deals with the identification of molecular changes with prognostic and therapeutic relevance in brain tumors. His work on the importance of the MGMT gene ( O6-methylguanine-DNA-methyltransferase ), the IDH gene ( glioblastoma ) and the BRAF gene ( Raf ) in gliomas and brain metastases, as well as the immune phenotype and the role of PD-L1 are often cited. He is co-author of the currently valid WHO classification of brain tumors, which is considered an internationally recognized standard reference. The oncologist is leading several clinical studies on cancer immunotherapy and an international, randomized therapy study on high-grade meningiomas .

Membership in international scientific associations

  • European Society of Medical Oncology
  • European Organization for Research and Treatment of Cancer
  • European Association of Neurooncology
  • Society of Austrian Neurooncology (founding member and first secretary)
  • Austrian Society for Hematology & Medical Oncology
  • Central European Cooperative Oncology Group

honors and awards

Publications

Books

  • Anton Luger, Leopold Öhler, Matthias Preusser (eds.): Internal medicine - symptoms and clinical problems. 2nd Edition. Facultas, 2010, ISBN 978-3-7089-0617-1 .

Web links

Individual evidence

  1. ^ Comprehensive Cancer Center
  2. ^ Executive and General Board. Retrieved September 26, 2019 .
  3. ^ M. Preusser, Charles R. Janzer, J. Felsberg, G. Reifenberger, MF Hamou, AC Diserens, R. Stupp, T. Gorlia, C. Marosi, H. Heinzl, JA Hainfellner, M. Hegi: Anti-O6 -methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker. In: Brain Pathol . 2008; 18: pp. 520-532. doi : 10.1111 / j.1750-3639.2008.00153.x .
  4. ↑ M. Preusser, A. Wöhrer, S. Stary, R. Höftberger, B. Streubel, JA Hainfellner: Value and limitations of immunohistochemistry and gene sequencing for detection of the IDH1-R132H mutation in diffuse glioma biopsy specimens. In: J Neuropathol Exp Neurol . 2011; 70: pp. 715-723. doi : 10.1097 / NEN.0b013e31822713f0 .
  5. ↑ D. Capper, AS Berghoff, M. Magerle, A. Ilhan, A. Wöhrer, M. Hackl, J. Pichler, S. Pusch, J. Meyer, A. Habel, P. Petzelbauer, P. Birner, A. von Deimling, M. Preusser: Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases. In: Acta Neuropathol . 2012; 123: pp. 223-233. doi : 10.1007 / s00401-011-0887-y .
  6. ↑ WHO brain tumor classification
  7. ↑ ESMO
  8. ↑ (EORTC)
  9. ↑ (EANO)
  10. ↑ (SANO)
  11. ↑ (ÖGHO)
  12. ↑ (CECOG)
  13. ↑ Researcher of the Month
  14. ↑ stiftung-sibylle-assmus.de ( Memento of the original from December 7, 2013 in the Internet Archive ) Info: The archive link has been inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.stiftung-sibylle-assmus.de
  15. ↑ docstoc.com
  16. ↑ meduniwien.ac.at
personal data
SURNAME Preusser, Matthias
BRIEF DESCRIPTION Austrian oncologist
DATE OF BIRTH October 29, 1976
PLACE OF BIRTH Mödling