Mycetoma

Classification according to ICD-10
B47	Mycetoma
ICD-10 online (WHO version 2019)

The mycetoma or mycetoma (also called Madura foot and Madura mycosis ) is a chronic granulation tumor that occurs primarily in the tropics , but also in the subtropics .

It is mainly caused by fungi that are introduced into a wound on the skin , for example from an injury with wood splinters or thorns when walking barefoot . In this case, it is called a eumycetoma . The pathogens include the fungal genera Madurella (especially Madurella mycetomatis ), Allescheria and Candida as well as Monosporium apiospermum and Scedosporium apiospermum . The incubation period ranges from several days to months. If, on the other hand, bacteria , for example from the genus Streptomyces or the Nocardia species Nocardia madurae , are the cause of the disease, it is referred to as an actinomycetoma . (This occurs mainly in Latin America as a painful form of mycetoma).

The diagnosis is made on the basis of the material obtained from the tumor by a surgical biopsy.

Therapy is especially the aktinomyzetische form of mycetoma initially with antibiotics ( sulfonamides , cotrimoxazole and streptomycin ). In the case of the fungus-related form, surgical treatment should primarily be carried out , if necessary also with beam resection .

literature

CMS Reis, EGM Reis-Filho: Mycetomas: an epidemiological, etiological, clinical, laboratory and therapeutic review. In: To Bras Dermatol. Volume 91, No. 1, 2018, pp. 8-18.
S. Venkatswami, A. Sankarasubramanian, S. Subramanyam: The madura foot: looking deep. In: Int J Low Extrem Wounds. Volume 11, No. 1, 2012, pp. 31-42.
Karl Wurm, AM Walter: Infectious Diseases. In: Ludwig Heilmeyer (ed.): Textbook of internal medicine. Springer-Verlag, Berlin / Göttingen / Heidelberg 1955; 2nd edition, ibid. 1961, pp. 9-223, here: p. 213.

Web links

BJ Anía: Mycetoma . On: emedicine.com. Version dated Jan. 8, 2007.
Altmeyer's Encyclopedia: Myzetom .

Individual evidence

↑ Thomas Grieser and others: Madura foot - have you seen it before? In: Bayerisches Ärzteblatt. Volume 75, No. 1–2, (January – February) 2020, p. 5.
↑ P. Nenoff, WW van de Sande, AH Fahal, D. Reinel, H. Schöfer: Eumycetoma - an update on causative agents, epidemiology, pathogenesis, diagnostics and therapy. In: J Eur Acad Dermatol Venerol. Volume 29, No. 1, 2015. pp. 1873-1883.
↑ O. Welsh include: mycetoma medical therapy. In: PLoS Negl Trop Dis. 8 (10), 2014, e3218.
^ HA Zein et al .: Predictors of cure, amputation and follow-up dropout among patients with mycetoma seen at the Mycetoma Research Center, University of Khartoum, Sudan. In: Trans R Soc Trop Med Hyg. Volume 106, No. 11, 2012, pp. 639-644.
↑ Thomas Grieser and others: Madura foot - have you seen it before? 2020.

[1] Thomas Grieser and others: Madura foot - have you seen it before? In: Bayerisches Ärzteblatt. Volume 75, No. 1–2, (January – February) 2020, p. 5.

[2] P. Nenoff, WW van de Sande, AH Fahal, D. Reinel, H. Schöfer: Eumycetoma - an update on causative agents, epidemiology, pathogenesis, diagnostics and therapy. In: J Eur Acad Dermatol Venerol. Volume 29, No. 1, 2015. pp. 1873-1883.

[3] O. Welsh include: mycetoma medical therapy. In: PLoS Negl Trop Dis. 8 (10), 2014, e3218.

[4] HA Zein et al .: Predictors of cure, amputation and follow-up dropout among patients with mycetoma seen at the Mycetoma Research Center, University of Khartoum, Sudan. In: Trans R Soc Trop Med Hyg. Volume 106, No. 11, 2012, pp. 639-644.

[5] Thomas Grieser and others: Madura foot - have you seen it before? 2020.