Osteopenia

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The osteopenia refers to a reduction in bone density , is a precursor to osteoporosis . However, not everyone diagnosed with osteopenia will develop osteoporosis.

Rather, osteopenia is defined as follows: the measured values ​​of bone density in osteopenia are between 1.0 and 2.5 standard deviations lower than an age- and gender-specific norm (= T-Score ). Even if osteoporosis is only considered to be osteoporosis from a measured value of 2.5 standard deviations, osteopenia already causes an increased risk of bone fractures.

Like osteoporosis, it is particularly common in postmenopausal women as a result of estrogen deficiency . The risk increases due to certain living conditions such as too little exercise, excessive alcohol consumption, smoking or the use of medication containing glucocorticoids for a longer period of time, such as those prescribed for certain respiratory and skin diseases.

If a change in diet and increased physical activity are not enough to treat osteopenia, medication can be used. The effect of the various preparations is, however, controversial among medical professionals. For example, tablets containing calcium and vitamin D , sodium fluoride and bisphosphonates are used .

To assess whether anti-resorptive therapy, e.g. B. is indicated with an aminobisphosphonate, the ten-year risk of an osteoporosis- related bone fracture or that of a bone fracture near the hip joint can be calculated using the computer-aided FRAX algorithm ( WHO Fracture Risk Assessment Tool ) and the data from a bone density measurement . Recommendations for therapy with aminobisphosphonate exist for a ten-year risk of 20% and 3%, respectively.

Web links

Wiktionary: Osteopenia  - explanations of meanings, word origins, synonyms, translations

Individual evidence

  1. ↑ Pablo Alonso-Coello, Alberto López García-Franco, Gordon Guyatt, Ray Moynihan: Drugs for pre-osteoporosis: prevention or disease mongering? In: British Medical Journal. (2008); 336, pp. 126-129. PMID 18202066 .
  2. ↑ A. Unnanuntana, BP Gladnick, E. Donnelly, JM Lane: The assessment of fracture risk. In: J Bone Joint surg. 2010; 92-A, pp. 743-753.