Pachydermia
| Classification according to ICD-10 | |
|---|---|
| L91.91 | Hypertrophic skin disease, unspecified |
| ICD-10 online (WHO version 2019) | |
The pachydermia (from ancient Greek παχύς pachys "thick, wide," and δερμα derma "skin") is an abnormal thickening and hardening of the skin or mucous membrane by hypertrophy of the interstitial connective tissue .
Synonyms are: elephant skin, pachyderma
The term is also used for precursors (epithelial hyperplasia) of vocal fold carcinoma .
Occurrence
Pachydermia is found in the following underlying diseases:
- Cutis verticis gyrata
- Pachydermoperiostosis
- Lichen myxedematosus
- Erythropoietic protoporphyria
- Scleromyxedema
Secondary in chronic edema , elephantiasis , non-Hodgkin lymphoma or leukemia
history
The term "pachydermia" (on the larynx) was coined by Rudolf Virchow in 1887.
literature
- P. Khera, JC English: Images in clinical medicine. Pachyderma. In: The New England Journal of Medicine . Volume 361, number 15, October 2009, p. E29, doi: 10.1056 / NEJMicm0805416 , PMID 19812397 .
Individual evidence
- ^ Willibald Pschyrembel : Clinical Dictionary , 266th, updated edition, de Gruyter, Berlin 2014, ISBN 978-3-11-033997-0
- ↑ a b Encyclopedia Dermatology
- ↑ a b Entry on pachydermia in Flexikon , a wiki of the DocCheck company
- ↑ E. Lebas, C. Chian, N. Nikkels-Tassoudji, JE Arrese, AF Nikkels: Pachyderma in Primary Cutaneous NK and T-Cell Lymphoma and Leukemia Cutis. In: Case reports in dermatology. Volume 9, number 3, 2017 Sep-Dec, pp. 151–157, doi: 10.1159 / 000480068 , PMID 29033820 , PMC 5637003 (free full text).
- ↑ R. Virchow: About Pachydermia laryngis, In: Berliner Klinische Wochenschrift, Vol. 24, 1887, pp. 585-589.
