Pathorama

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Pathorama is a freely accessible online pathology learning environment for various target groups. In the German-speaking area there are so far only a few freely accessible offers for basic, advanced and advanced training in the field of pathology. Pathorama consists of online learning and information modules as well as tools for self-evaluation, which cover all areas of pathology ( autopsy , macroscopy , histology , cytology ) and complement or build on each other. In 2007 the name was changed from PathoBasiliensis to Pathorama. The PathoBasiliensis project was awarded the MEDIDA-PRIX in 2004.

construction

Pathorama consists of the following components:

PathoPic Image database; Basis for most of the other modules German and English
HiPaKu Histopathology course; for medical students German
ZyPaKu Cytopathology course; for doctors and laboratory technicians German
vSlides virtual histological slides English
vCollections thematic collections of virtual histological specimens English
Autopsy case database Case database; for students and doctors German
MatchingPair Game for self-evaluation; interdisciplinary German

Pathorama has a modular structure. PathoPic and vSlides are basic modules that are reused in modules based on them (e.g. HiPaKu, vCollections). HiPaKu, for its part, can be adapted to other universities with minimal effort and has already been implemented for 5 universities. Other modules (e.g. MatchingPair, vCollections) are designed in such a way that they can be used by different departments through pure parameterization. The Pathorama concept allows for a modular, cost-effective and maintenance-friendly implementation of online learning materials. These aspects are the prerequisite for a feasible, i. H. affordable and sustainable transferability to other subjects, also outside of pathology and medicine.

Applications of tools from Pathorama

In addition to the student training and pathology-specific applications documented in detail under literature, there are other possible applications:

  • Images and virtual preparations are used for documentation
  • Research in the field of artificial intelligence, image recognition.

Historical background

In 1998, when Katharina Glatz began her specialist training as a pathologist, she found that good image material in this visually strongly influenced discipline was only available sparingly and / or in expensive books. Her husband Dieter Glatz, as the deputy head of the university data center, is heavily involved in the provision of the new Internet technologies and they are creating a freely accessible website for training. First, an autopsy case database with 120 cases is created. The two quickly realized that visual material had to be provided in a modular, reusable form in order to be able to efficiently build up learning modules. The result is PathoPic, an image database that now provides over 10,000 images from macroscopy, histology and cytology.

While other image collections were automatically scanned and posted on the web, PathoPic carefully selected each image and provided metadata according to thesaurus-based categories. This enables targeted searches and finding of relevant images on a given topic.

1999 Development of HiPaKu. With the HistoPathology course, students learn intensively to prepare for exams. A cytopathology course (ZyPaKu) and educational games (e.g. MatchingPair) complete the offer.

In 2000 a new - didactic - challenge arises: the picture material that is now sufficiently available is extremely instructive, but can not replace searching and finding with self-selected setting of different magnifications on the microscope. But it is precisely this - exploratory - approach on the microscope that is an important component of the learning process. A virtual microscope offers a solution . A histology specimen is completely scanned. It can then be viewed by any number of users via the Internet on the computer, regardless of time and place. Virtual specimens are huge: 260,000 × 160,000 pixels (around 125 GB of raw data per image). Commercial products do not yet exist at this point in time. With a grant from the Renewal Fund of the University of Basel , a first virtual microscope (vMic) was designed and programmed, which went into operation in 2002.

The various learning tools and modules are combined into a common learning platform under the name PathoBasiliensis . The name is made up of pathology and Universitas Basiliensis , the Latin name of the University of Basel, which was founded in 1460.

Up to this point, with the exception of the grant from the renewal fund for the procurement of a microscope, the lion's share of all contributions had been made by the initiators on a private basis.

2004 Winning the MEDIDA-PRIX 2004.

In 2006, the initiators of the 4th framework program of the Swiss Virtual Campus received funds to build a new version of the virtual microscope and a database for virtual histology slides (vSlides) and virtual cutting seminars (vCollections). The university data center acts as an official university partner, where Tobias Marquart and Gilbert Francz, among others, contribute to the realization of the new project.

In 2007 PathoBasiliensis underwent a redesign and name change. Existing and new tools are now available under the name Pathorama. The name change is a reaction to the increasing internationalization of the offer.

Awards

PathoBasiliensis has received several awards. The highlight was winning the highest endowed European competition for e-learning projects in the university sector MEDIDA-PRIX 2004, where PathoBasiliensis won first prize from 187 participants from Germany, Austria and Switzerland.

Publications

Publications on quizzes

In these publications, specialists were interviewed with a quiz module. The assessed images and virtual specimens come from PathoPic and vSlides:

  • K. Glatz, S. Savic, D. Glatz, G. Francz, A. Barascud, B. Grilli, M. Herzog, P. Dalquen, G. Feichter, P. Player, M. Tamm, L. Bubendorf: An Online Quiz Uncovers Limitations of Morphology in Equivocal Lung Cytology. In: Cancer Cytopathology . Volume 108, No. 6, 2006, pp. 480-487.
  • KJ Butnor, RT Vollmer, H. Blaszyk, K. Glatz: Interobserver agreement on what constitutes visceral pleural invasion by non-small cell lung carcinoma: an internet-based assessment of international current practices. In: Am J Clin Pathol . Volume 128, No. 4, 2007, pp. 638-647.
  • K. Glatz, B. Pritt, D. Glatz, A. Hartmann, J. O'Brien, H. Blaszyk: Variability in the Assessment of Serrated Colorectal Polyps. In: Am J Clin Pathol. Volume 128, No. 2, 2007, p. 348.
  • K. Glatz, N. Willi, D. Glatz, A. Barascud, B. Grilli, M. Herzog, P. Dalquen, G. Feichter, T. Gasser, T. Sulser, L. Bubendorf: An International Telecytological Quiz on Urinary Cytology Uncovers Educational Deficits and Absence of a Commonly Used Classification System. In: Am J Clin Pathol. Volume 126, No. 2, 2006, pp. 1-8.

Publications on Pathorama

Publications where the possible uses of Pathorama (PathoBasiliensis) in education and research were reported:

  • K. Glatz, L. Bubendorf, D. Glatz: Cytology on the Internet. In: The Pathologist. Volume 28, No. 5, 2007, pp. 318-324.
  • K. Glatz-Krieger, D. Glatz, MJ Mihatsch: Virtual Microscopy: First applications. In: The Pathologist. Volume 27, No. 6, 2006, pp. 469-476.
  • K. Glatz-Krieger, U. Spornitz, A. Spatz, MJ Mihatsch, D. Glatz: Factors to Keep in Mind when Introducing Virtual Microscopy. In: Virchow's archive. Volume 448, 2006, pp. 248-255.
  • K. Glatz, D. Glatz: The PathoBasiliensis learning platform. In: Swiss Medical Informatics. Volume 56, 2005, pp. 7-10.
  • K. Glatz-Krieger, D. Glatz, M. Gysel, M. Dittler, MJ Mihatsch: Web-based learning tools for pathology. In: The Pathologist. No. 5, 2003, pp. 394-399.
  • K. Glatz-Krieger, D. Glatz, MJ Mihatsch: Virtual Slides: High-Quality Demand, Physical Limitations, and Affordability. In: Human Pathology . Volume 34, No. 10, 2003, pp. 968-974.
  • D. Glatz, K. Glatz-Krieger, MJ Mihatsch: Database-based web projects. In: Swiss Review for Medicine PRAXIS. Volume 88, 1999, pp. 691-697.
  • K. Glatz-Krieger, D. Glatz, MJ Mihatsch: Autopsies on the Internet; A web-based tool for teaching. In: Swiss Review for Medicine PRAXIS. Volume 88, 1999, pp. 498-503.

Web links

Individual evidence

  1. a b PathoPic
  2. a b HiPaKu - Histopathology course
  3. a b ZyPaKu - Cytopathology course
  4. a b vSlides - virtual histology slides
  5. a b vCollections - virtual editing seminars
  6. a b Autopsy case database
  7. a b MatchingPair
  8. Improving Performance of Medical Images Retrieval by Combining Textual and Visual Information (PDF)
  9. vMic - virtual microscope from 2002
  10. a b MEDIDA-PRIX 2004, winner | Homepage
  11. Swiss Virtual Campus