Phenyl mercuriborate
Phenylmercury (also phenylmercuric borate, Phenylhydrargyriboras, Orthoboratophenylquecksilber) is a mixture of equimolar amounts of -orthoborat phenylmercuric (II) and phenyl mercury (II) hydroxide (C 12 H 13 BHg 2 O 4 ) or the dehydrated form (metaborate, C 12 H 11 BHg 2 O 3 ) or a mixture of the first mixture and the metaborate.
properties
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| Surname |
Phenyl mercuriborate |
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| CAS number |
8017-88-7 |
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| EC number |
203-068-1 |
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It is in the form of a white to slightly yellowish, crystalline powder or as colorless, shiny crystals, which are only sparingly soluble in water. The melting point is 112–113 ° C.
use
Until the 1990s, phenyl mercuriborate was used, among other things, as an active ingredient in disinfectants and in the area of wound treatment for the skin and in the oropharynx, for example under the trade name Merfen . Due to the high mercury content in this application, the active ingredient was replaced by other mercury-free substances. Phenyl mercuriborate is used in concentrations of 0.001% to 0.002% as a preservative in eye drops .
Individual evidence
- ↑ European Pharmacopoeia, 8th edition, Grundwerk 2014, p. 4537. Deutscher Apotheker Verlag, Stuttgart.
- ^ Entry on organic mercury compounds in the GESTIS substance database of the IFA , accessed on April 26, 2017 (JavaScript required)
- ↑ Not explicitly listed in Regulation (EC) No. 1272/2008 (CLP) , but with the specified labeling it falls under the group entry organic compounds of mercury with the exception of those specified elsewhere in this Annex in the Classification and Labeling Inventory of the European Chemicals Agency ( ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
- ^ A b c Franz v Bruchhausen, Gerd Dannhardt, Siegfried Ebel, August-Wilhelm Frahm, Eberhard Hackenthal: Hager's handbook of pharmaceutical practice . Springer-Verlag, 2013, ISBN 978-3-642-57880-9 , pp. 176–178 ( limited preview in Google Book search).
