Remodeling

Cellular remodeling processes that occur in connection with physiological development processes can be referred to as remodeling or remodeling . They are often the result of illnesses or injuries. Structure-changing cells such as fibroblasts are activated, migrate into damaged tissue areas and change them, often in the sense of a loss of function, in particular a hardening. In conjunction with remodeling, it is also possible to regenerate the original function, so physical training can improve the function again. Remodeling can also refer to bone remodeling or angiogenesis .

See also

• Mechanostat

Individual evidence

1. ↑ Chistiakov DA et al .: The role of cardiac fibroblasts in post-myocardial heart tissue repair. Exp Mol Pathol. 2016 Oct; 101 (2): 231-240. doi: 10.1016 / j.yexmp.2016.09.002 .
2. ↑ Virpi Talman et al .: Cardiac fibrosis in myocardial infarction — from repair and remodeling to regeneration, Cell Tissue Res. 2016; 365 (3): 563-581. doi: 10.1007 / s00441-016-2431-9 . PMC 5010608 (free full text)
3. ↑ Tiago Fernandes et al .: Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs, American Journal of Physiology - Heart and Circulatory Physiology Published 15 August 2015 Vol. 309 no. 4, H543-H552. doi: 10.1152 / ajpheart.00899.2014 .

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