Antifibrinolytic

Antifibrinolytic agents act by inhibition of fibrinolysis in the blood, d. that is, they cause a reduced breakdown of the thrombus and thus an increased coagulation .

They are therefore used in cases of increased fibrinolysis , excessive fibrinolytic therapy and complications during childbirth.

Pharmaceuticals

• Aprotinin : inhibits plasmin, kallikreine, trypsin, chymotrypsin. The onset of action is quick.
• ε-aminocaproic acid , para- aminomethylbenzoic acid (PAMBA), tranexamic acid : inhibition of plasminogen activators. The onset of action is slow here.