Axotomy

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Axotomy describes the process of (artificial) severing of nerves e.g. B. by cutting. The fact that the transection is intentional is what distinguishes axotomy from axonotmesis .

Axotomy is often used in neurobiological research, for example to examine the regenerative capacity in the nervous system and to find ways to combat neurodegenerative diseases.

An axotomy can lead to Waller's degeneration in the distal direction .

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Dunlop et al., 2007. Regenerating Optic Axons Restore Topography after Incomplete Optic Nerve Injury. The Journal of Comparative Neurology 505: 46-57