Isabel le Despenser
Isabel le Despenser is the name of the following people:
- Isabel le Despenser (noblewoman, around 1290) (around 1290–1334), English nobleman
- Isabel le Despenser (noblewoman, around 1313) (around 1313–1375), English nobleman
- Isabel le Despenser, 5th Baroness Burghersh (1400–1439), English nobleman