James Guthrie
James Guthrie is the name of the following people:
- James Guthrie (politician, 1792) (1792–1869), American politician
- James Guthrie (painter) (1859-1930) Scottish artist
- James Guthrie (politician, 1872) (1872-1958), Australian politician
- James Guthrie (producer) (born 1953), British music producer