Kashin-Beck disease

from Wikipedia, the free encyclopedia
Classification according to ICD-10
M12.- Other specified arthropathies
M12.1- Kashin-Beck disease
ICD-10 online (WHO version 2019)

The Kashin-Beck disease (also Cashing-Beck disease , osteoarthropathy with dwarfism or nutritive articular cartilage degeneration ) is a deficiency disease that was named after the Russian military doctors Nikolai Ivanovich Kashin (1825–1872) and Evgeny Vladimirovich Bek (1865–1915). It occurs endemicallyin Northeast Siberia, North China, Tibet, Mongolia and North Korea, where around 3 million people are affected. Around the age of 5, symmetrical deformations of the joints of the arms and legs appear due to the inhibition of skeletal growth. In the above-mentioned countries, the term "large bone disease" is therefore also used. Those affected also suffer from short stature and occasionally from bleeding.

A selenium deficiency is discussed as the cause . However, selenium substitution does not have a positive effect on an existing disease. Since Kashin-Beck disease also affects the thyroid gland , substitution with iodine can make sense.

Individual evidence

  1. W. Forth, D. Henschler, W. Rummel: General and special pharmacology and toxicology . 9th edition. URBAN & FISCHER, Munich 2005, ISBN 3-437-42521-8 .