Coagulopathy

Classification according to ICD-10
D65-D69	Coagulopathies, purpura and other hemorrhagic diatheses
ICD-10 online (WHO version 2019)

As coagulopathy (from Latin coagulatio "clotting" and from Greek and πάθος, páthos "passion, addiction, pathos") or coagulation disorder is a disorder of blood clotting ( hemostasis ) in medicine . An increased tendency to bleed ( haemorrhagic diathesis ) with reduced blood clotting is called minus coagulopathy , and increased blood clotting (hypercoagulability) is called plus coagulopathy . By definition, coagulopathies are caused by a deficiency or disruption of the coagulation factors .

It can congenital from acquired causes as well as quantitative (absence or reduction of coagulation factors) and quality (defects of the coagulation factors) coagulopathies be distinguished.

Congenital negative coagulopathies are, for example, hemophilia and Von Willebrand-Jürgens syndrome .

Acquired minus coagulopathies occur, for example, in consumption coagulopathies , diseases of the liver (reduced synthesis of coagulation factors, e.g. prothrombin complex deficiency ), vitamin K deficiency (reduced synthesis of vitamin K-dependent coagulation factors) and inhibitor hemophilia .

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• H. Renz-Polster, S. Krautzig: Basic textbook internal medicine . Urban & Fischer-Verlag Munich 2008, 4th edition, p. 342 ff. ISBN 978-3-437-41053-6 .
• Pschyrembel - Clinical Dictionary , 259th edition, Walter de Gruyter, Berlin, 2002, ISBN 3-11-016522-8 .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !