Neonatal abstinence syndrome
| Classification according to ICD-10 | |
|---|---|
| P96.1 | Withdrawal symptoms in the newborn when the mother takes addiction-inducing drugs or drugs |
| ICD-10 online (WHO version 2019) | |
In medicine, neonatal abstinence syndrome is a symptom of withdrawal in newborns of drug-dependent mothers. This leads to tremors , muscle hypertension, short periods of sleep, high-pitched screaming and gastrointestinal symptoms such as vomiting or diarrhea. Respiratory disorders are to be expected, especially when consuming hard drugs. The incidence of acute respiratory distress syndromes in these infants is increased.
In the United States, it affects between 6.0 and 20 newborns per 1,000 live births. There are significant differences in the diagnosis and treatment of neonatal abstinence syndrome.
In studies, mostly morphine , rarely methadone, or diluted opium tincture were used for therapy. The authors of a current literature review of these studies from 2007 and 2017 come to the conclusion that the evidence for the optimal diagnostic and treatment strategies for neonatal abstinence syndrome is based on small or methodologically weak studies that use indirect parameters such as the Need for pharmacological treatment or length of hospital stay.
literature
- Iris Edenhofer: The newborn in the midwifery practice. 2nd updated edition, Hippokrates Verlag, Stuttgart 2010, ISBN 978-3-8304-5441-0 , p. 142 ff.
- Michael Ehlen (Ed.): Clinical standards for neonatology and pediatric intensive care medicine. Georg Thieme Verlag, Stuttgart 2014, ISBN 978-3-13-173821-9 , pp. 140 ff.
Web links
- Neonatal Withdrawal Syndrome (accessed February 19, 2016)
- Newborns and Drug Addicted Mothers (accessed February 19, 2016)
- Legal and Illegal Drugs During Pregnancy (accessed February 19, 2016)
Individual evidence
- ^ A b Elisha M. Wachman, Davida M. Schiff, Michael Silverstein: Neonatal Abstinence Syndrome: Advances in Diagnosis and Treatment . In: JAMA . tape 319 , no. 13 , April 3, 2018, ISSN 1538-3598 , p. 1362-1374 , doi : 10.1001 / jama.2018.2640 , PMID 29614184 .
