Niosome

Niosomes ( N on- io nic s urfactants) are the liposomes similar microscopically small spheres, in which a double-membrane encloses an interior space. Active ingredients can be incorporated into this interior space . The covering with the double membrane protects sensitive active ingredients and can improve their transport. Niosomes also play an important role in research, since lipophilic substances can be used in an aqueous medium in a cell culture with the help of the niosomes.

history

Niosomes are first mentioned in the 1970s and were initially used in the cosmetic industry.

Differences from liposomes

Niosomes are structured analogously to liposomes. However, liposomes contain double membranes formed from phospholipids , whereas the building blocks of the niosome double membrane are derived from sugars or amino acids .

Individual evidence

↑ Vanlerberghe, G., Handjani-Vila, R.-M., Berthelot, C. and Sebag, H., 1972, chemistry, physical chemistry and application engineering of surface-active substances. Reports from Vi. International Congress for Surface-Active Substances Carl Hanser Verlag, Zurich.

literature

Non-ionic surfactant based vesicles (niosomes) in drug delivery ; In: International Journal of Pharmaceutics , Volume: 172, Issue: 1-2, pp. 33-70, October 1998

[1] Vanlerberghe, G., Handjani-Vila, R.-M., Berthelot, C. and Sebag, H., 1972, chemistry, physical chemistry and application engineering of surface-active substances. Reports from Vi. International Congress for Surface-Active Substances Carl Hanser Verlag, Zurich.