Open study

A clinical study is called an open study (also: open-label study or open-label study ) if the study participants, the therapist and the staff involved know which therapy the study participants are receiving. Nevertheless, it is usually possible and recommended to evaluate an open study by blind evaluators. This means that the evaluators do not know which treatment the person to be assessed received.

Open studies are often used in therapies in the early stages of development, mostly in clinical phases I and II.

Individual evidence

↑ The concept of “blinding” in clinical studies. In: European Patients Academy. Retrieved August 1, 2020 .
↑ open label study. In: National Cancer Institute. Retrieved August 1, 2020 .
↑ ^a ^b Philip Sedgwick: What is an open label trial? (= British Medical Journal . G3434, No. 348 ). May 23, 2014, doi : 10.1136 / bmj.g3434 (English, bmj.com [accessed August 1, 2020]).
↑ Kenneth F. Schulz, David A. Grimes: Series Epidemiology 8: Blinding in randomized studies: How to cover up who has received what (= Journal for Medical Training and Quality in Health Care . Volume 9 , no. 101 ). December 20, 2007, p. 630–637 , doi : 10.1016 / j.zgesun.2007.09.024 ( sciencedirect.com [accessed August 1, 2020]).

[1] The concept of “blinding” in clinical studies. In: European Patients Academy. Retrieved August 1, 2020 .

[2] open label study. In: National Cancer Institute. Retrieved August 1, 2020 .

[Sedgwick-3] Philip Sedgwick: What is an open label trial? (= British Medical Journal . G3434, No. 348 ). May 23, 2014, doi : 10.1136 / bmj.g3434 (English, bmj.com [accessed August 1, 2020]).

[4] Kenneth F. Schulz, David A. Grimes: Series Epidemiology 8: Blinding in randomized studies: How to cover up who has received what (= Journal for Medical Training and Quality in Health Care . Volume 9 , no. 101 ). December 20, 2007, p. 630–637 , doi : 10.1016 / j.zgesun.2007.09.024 ( sciencedirect.com [accessed August 1, 2020]).