Ronald M. Evans

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Ronald Mark Evans (born April 17, 1949 in East Los Angeles ) is an American molecular biologist and physiologist at the Salk Institute for Biological Studies and at the University of California, San Diego , and Howard Hughes Medical Institute Investigator .

Life

Evans earned a bachelor's degree in bacteriology from the University of California, Los Angeles in 1970 and a Ph.D. in microbiology . From 1975 to 1978 he was a post-doctoral student at Rockefeller University in New York City with James E. Darnell . He received his first junior professorship ( Assistant Professor 1978, Associate Professor 1983) at the Salk Institute for Biological Studies . Evans took on his first ( adjunct ) professorship (adjunct professor) at a university in 1985 at the University of California in San Diego in the Department of Biology , in 1989 in the School of Medicine, Department of Biomedical Sciences , and since 1995 in the Department of Neurosciences . Evans has also been a professor at the Salk Institute since 1986 , where he has been chairman of the faculty on several occasions.

Act

In 1986 , Pierre Chambon and Ronald M. Evans independently cloned the nuclear receptors for thyroid hormones ( thyroid hormone receptor ) and glucocorticoids ( glucocorticoid receptor ), for which they together with Elwood V. Jensen , who discovered the estrogen receptor in 1958, with the Albert Lasker Award for Basic Medical Research 2004 were awarded. As a result of this work, numerous other hormone receptors and nuclear receptors were discovered that play important functions in energy , fat and muscle metabolism, in metabolic diseases , in the regulation of inflammatory processes and in cancer diseases and which are suitable as target molecules for appropriate therapies.

Awards (selection)

Evans received numerous other scientific awards; He is a member of several other scientific societies and co-editor of several scientific journals.

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Individual evidence

  1. ^ Albert Lasker Basic Medical Research Award. Pierre Chambon, Ronald Evans and Elwood Jensen. For the discovery of the superfamily of nuclear hormone receptors and elucidation of a unifying mechanism that regulates embryonic development and various metabolic pathways. laskerfoundation.org; Retrieved October 23, 2010
  2. ^ Nuclear Receptors in Physiology and Disease. hhmi.org; Retrieved October 28, 2010
  3. Ronald M. Evans PhD at the Gairdner Foundation (gairdner.org); Retrieved December 14, 2012
  4. The NOMIS Foundation - Ronald M. Evans. In: nomisfoundation.ch. April 9, 2020, accessed June 1, 2020 .