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Seche or Seché or Séché is the family name of the following people:
- Alphonse Séché (1876–1964), French writer and literary critic
- Josef Seché (architect) (actually Josef Sechehaye ; 1850–1901), German architect and teacher
- Josef Seché (painter) (actually Emil Josef Karl Sechehaye ; 1880–1948), German painter and graphic artist
- Léon Seché (1848–1914), French publicist
- Luiza Seche (* 1926), Romanian romance scholar
- Mircea Seche (* 1924), Romanian Romanist
- Stephen Seche (* 1952), American diplomat
See also:
- Bretagne-Séché Environnement , French cycling team
- Sech (agricultural engineering) , component of a plow
