Tetrasomy

A tetrasomy ( Greek τετρα- four and σώμα "body", here chromosome body as the carrier of the genetic information) is when, due to an unusual meiotic division of the egg cell or sperm, one chromosome or part of a chromosome is fourfold ( tretraom ) instead of twofold ( disome ) present in all or some of the body's cells.

A general distinction is made between simple tetrasomy (only one chromosome is quadrupled) and multiple tetrasomy (several chromosomes are quadrupled).

In essence, the details presented in the main article Trisomy apply analogously to the tetrasomy . In principle, more pronounced phenotypic effects are to be expected in a tetrasomy than in a trisomy.

Tetrasomy syndromes

The structural chromosomal aberrations occurring in humans include tetrasomy 22p ( cat's eye syndrome ) and tetrasomy 12p ( Pallister-Killian syndrome ).

Individual evidence

1. ^ R. Witkowski et al.: Lexicon of syndromes and malformations: causes, genetics, risks. Springer, 2003, ISBN 3-540-44305-3 , p. 244, (online)

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !