Central sensitization

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The concept of central sensitization describes the changed activity of the neurons that process pain in the central nervous system , whereby pain is intensified ( hyperalgesia ) and also normally non-painful stimuli such as touch trigger pain ( allodynia ). Central sensitization probably contributes to the maintenance of chronic pain in various diseases. These include rheumatoid arthritis and osteoarthritis , fibromyalgia , headache, neuropathic pain , complex regional pain syndromes and pain after surgery.

See also

supporting documents

  1. ^ Clifford J. Woolf: Central Sensitization: Implications for the diagnosis and treatment of pain . In: Pain . tape 152 , Supplement, March 2011, ISSN  0304-3959 , p. S2 – S15 , doi : 10.1016 / j.pain.2010.09.030 , PMID 20961685 , PMC 3268359 (free full text) - ( wkhealth.com [accessed June 6, 2018]). Alban Latremoliere, Clifford J. Woolf: Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity . In: The Journal of Pain . tape
     10 , no. 9 , September 2009, ISSN  1526-5900 , p. 895-926 , doi : 10.1016 / j.jpain.2009.06.012 , PMID 19712899 , PMC 2750819 (free full text) - ( elsevier.com [accessed June 6, 2018]).