Bärbel Friedrich

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Bärbel Friedrich (born July 29, 1945 in Göttingen ) is a German microbiologist.

Friedrich studied biology at the University of Göttingen with a diploma in 1970 and a doctorate in microbiology in 1973 with Hans Günter Schlegel ( regulation of the biosynthesis of phenylalanine and tyrosine in Hydrogenomonas eutropha strain H 16 ). As a post-doctoral student , she was at the Massachusetts Institute of Technology in 1975/76 and then continued research at the Institute for Microbiology in Göttingen, where she completed her habilitation in 1983. In 1985 she became Professor of Microbiology at the Free University of Berlin and from 1994 at the Humboldt University in Berlin . Since 2008 she has been the Scientific Director of the Alfried Krupp Science College in Greifswald .

She is particularly concerned with the function and biosynthesis of metal proteins, catalysis of hydrogenases and their application in biotechnology and functional genome analysis in bacteria. Among other things, she examined hydrogen production by the aerobic bacterium Ralstonia eutrophia (which uses nickel-iron-containing hydrogenases) and the development of natural or natural-mimicking (biomimetic) systems for hydrogen production based on it. Hydrogen production via bacteria has long been the focus of research because of its potential use as a fuel. Although the use of hydrogen as an energy source probably played a major role in the early days of life and extremophilic bacteria ( archaea ), which are considered to be the closest relatives of the first life forms on earth, usually have appropriate enzymes, the control of hydrogen use in higher bacteria is that use hydrogen only as an additional energy source, as Friedrich and colleagues found, quite complex and probably represents an evolutionary new development. This also requires sensor mechanisms for hydrogen in the bacterium, which is a particular challenge for the bacterial cells due to the small size of the hydrogen molecules represents.

She is group leader in the Cluster of Excellence of the DFG Unifying Concepts in Catalysis in the field of analysis of the structure and function of oxygen-tolerant hydrogenases.

She is a member of the Berlin-Brandenburg Academy of Sciences (1994) and the Leopoldina (1994), of which she has been vice-president since 2005. In addition, she has been a corresponding member of the Göttingen Academy of Sciences since 2000 , a corresponding member of the North Rhine-Westphalian Academy of Sciences since 1997 and was Vice President of the German Research Foundation (DFG) from 1997 to 2003. From 2003 to 2005 she was a member of the parliamentary study commission for medical ethics. In 2013 she received the Cross of Merit on Ribbon of the Federal Republic of Germany and in 2016 the Leopoldina Medal of Merit .

Web links

Individual evidence

  1. Oliver Lenz, Bärbel Friedrich: Bacterial Hydrogen Sensors , BioSpektrum, Volume 7, pdf
  2. ^ Member entry of Bärbel Friedrich (with picture and CV) at the German Academy of Natural Scientists Leopoldina , accessed on July 6, 2016.
  3. Order of Merit 2013