Barry Trost

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Barry M. Trost (June 2012)

Barry M. Trost (born June 13, 1941 in Philadelphia ) is an American chemist and professor of chemistry at Stanford University .

life and work

He graduated from the University of Pennsylvania . For his dissertation on the structure and reactivity of enolate anions , he moved to the Massachusetts Institute of Technology in the group of Herbert O. House . He was a professor at the University of Wisconsin from 1965 to 1987 and then moved to Stanford University.

The Tsuji Trost Reaction and the Trost Ligand are named after him. According to his own statements, he is one of the 50 most frequently cited chemists in the world.

The research focus is on synthesis, whereby the development of new reactions and reagents as well as the development of a network of reactions (see also tandem reaction ) in order to build complex target molecules from simple molecules. For the development of new reactions the route of the so-called chemical enzymes is pursued, which are non-peptide transition metal-based catalysts with chemo-, regio- and enantioselective properties. Target molecules include ring compounds with more than six ring members produced by metal catalysis.

Honors, prizes and memberships (selection)

Publications (selection)

Reference books

  • ML Crawley, BM Trost: Applications of Transition Metal Catalysis in Drug Discovery and Development. John Wiley & Sons, 2012, ISBN 1-118-30983-9 limited preview in Google Book Search
  • BM Trost: Stereocontrolled Organic Synthesis. Blackwell Scientific Publications, 1994, ISBN 0-86542-833-6
  • BM Trost, MF Semmelhack, I. Fleming: Comprehensive Organic Synthesis: Additions to and Substitutions at CC Pi-Bonds. Verlag Elsevier, 1991, ISBN 0-08-040595-9 limited preview in Google Book Search
  • BM Trost: Problems in Spectroscopy , WA Benjamin Co., 1977
  • BM Trost, LS Melvin: Sulfur Ylides - Emerging Synthetic Intermediates , Academic Press, 1975, ISBN 0-12-701060-2

Technical article

Web links

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