Vasculopathy

Classification according to ICD-10
M31	Other necrotizing vasculopathies
M31.0	Hypersensitivity angiitis, including Goodpasture syndrome
M31.1	Thrombotic microangiopathy, including thrombotic thrombocytopenic purpura [Moschkowitz]
M31.2	Fatal midline granuloma
M31.3	Wegener's granulomatosis, including necrotizing granulomatosis of the airways
M31.4	Aortic arch syndrome [Takayasu syndrome]
M31.5	Giant cell arteritis in polymyalgia rheumatica
M31.6	Other giant cell arteritis
M31.7	Microscopic polyangiitis excluding polyarteritis nodosa (M30.0)
M31.8	Other specified necrotizing vasculopathies, including hypocomplementemic (urticarial) vasculitis
M31.9	Necrotizing vasculopathy, unspecified
ICD-10 online (WHO version 2019)

Vasculopathies ( vas = "the vessel", suffix - pathie = 'disease') (syn. Angiopathy ) are a group of primarily non- inflammatory vascular diseases of various causes that lead to a partial or complete occlusion of a vessel. In necrotizing vasculopathies , the vascular occlusion leads to necrosis , the pathological destruction of cells and the surrounding tissue.

In contrast to this, vasculitis ( singular : vasculitis , suffix - itis = 'inflammatory disease') are inflammatory vascular diseases. In practice, however, the two disease types are often not properly separated from one another. For example, granulomatosis with polyangiitis and giant cell arteritis , both diseases with an inflammatory (inflammatory) etiology, are classified as necrotizing vasculopathies according to ICD-10 .

Small vessel vasculopathies

Coumarin necrosis is a vasculopathy

• Vasculopathies with disseminated intravascular coagulopathy (consumption coagulopathy). These are diseases with excessively strong blood clotting in the blood vessel system, which can lead to the blood vessels becoming blocked.
  • Purpura fulminans
  • Waterhouse-Friderichsen Syndrome
  • Coumarin necrosis
  • heparin-induced thrombocytopathy
  • Phospholipid Antibody Syndrome
  • Thrombotic thrombocytopenic purpura
• Paroxysmal nocturnal hemoglobinuria
• Acroangiodermatitis
• Livedovasculopathy
• Lymphedema
• Reactive angioendotheliomatosis

In organ transplants, graft vasculopathies in the transplanted organ can lead to chronic organ rejection. Some authors see connections between migraines and different vasculopathies which allow the migraine to be viewed as systemic vasculopathy.

Medium vessel vasculopathies

• Livedo racemosa
• Calciphylaxis
• Arteriosclerosis or arteriolosclerosis
• Cholesterol embolism syndrome
• Embolia cutis medicamentosa
• Aortic arch syndrome

See also

• Fowler syndrome - cerebral vasculopathy with hydrocephalus

Individual evidence

1. ↑ P. Altmeyer: Entry on vasculopathy in the encyclopedia of dermatology, venereology, allergology, environmental medicine. Springer-online, accessed November 15, 2018
2. ↑ Graft vasculopathy.  ( Page no longer available , search in web archives )  Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. LMU Munich, accessed on February 2, 2012  
3. ↑ MS Lee, W. Finch et al .: Cardiac allograft vasculopathy. In: Reviews in cardiovascular medicine. Volume 12, Number 3, 2011, pp. 143-152, ISSN  1530-6550 . PMID 22080925 . (Review).
4. ↑ AH Stam, J. Haan et al: Migraine and genetic and acquired vasculopathies. In: Cephalalgia: an international journal of headache. Volume 29, Number 9, September 2009, pp. 1006-1017, ISSN  1468-2982 . doi: 10.1111 / j.1468-2982.2009.01940.x . PMID 19689610 . (Review).
5. ^ GE Tietjen: Migraine as a systemic vasculopathy. In: Cephalalgia. Volume 29, Number 9, September 2009, pp. 987-996, ISSN  1468-2982 . doi: 10.1111 / j.1468-2982.2009.01937.x . PMID 19689607 . (Review).