Tositumomab: Difference between revisions

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'''Tositumomab''' is a [[monoclonal antibody]] derived from immortalized mouse cells. It is a IgG2a anti-CD20 antibody and is covalently bound to Iodine 131. 131I emits both beta and gamma radiation, and is broken down rapidly in the body.
'''Tositumomab''' is a [[monoclonal antibody]].


Clinical trials have established the efficacy of tositumomab in patients with relapsed follicular lymphoma.
{{treatment-stub}}

It is manufactured by [[Corixa]]. It sells in the U.S. under the trade name Bexxar.{{treatment-stub}}

Revision as of 00:52, 23 November 2006

Tositumomab
File:Tositumomab.png
Identifiers
  • Murine anti-CD20 antibody
CAS Number
DrugBank
Chemical and physical data
FormulaC6416H9874N1688O1987S44
Molar mass143859.7 g/mol

Tositumomab is a monoclonal antibody derived from immortalized mouse cells. It is a IgG2a anti-CD20 antibody and is covalently bound to Iodine 131. 131I emits both beta and gamma radiation, and is broken down rapidly in the body.

Clinical trials have established the efficacy of tositumomab in patients with relapsed follicular lymphoma.

It is manufactured by Corixa. It sells in the U.S. under the trade name Bexxar.