HCP
- H. Cegielski - Poznań S.A., a Polish manufacturing company
- Habitat Conservation Plan
- High Card Points, a contract bridge term
- Health Care Property Investors, Inc. US healthcare real estate investment company
- Hereditary coproporphyria, a deficiency disease
- Hexagonal close-packed arrangement of spheres
- Hitachi Content Platform
- Hot copy, a Linux command line utility (hcp)
- Methylidynephosphane, a molecule with the chemical formula CHP