Alfonso Rodriguez
Alfonso Rodriguez may refer to:
- Alphonsus Rodriguez (1532–1617), Jesuit brother, Roman Catholic Saint
- Alphonsus Rodriguez (martyr) (1598-1628), Jesuit saint
- Alonso Rodriguez (1526-1616), author of The Practice of Christian and Religious Perfection
- Alfonso Rodríguez (athlete), Mexican athlete in 1977 Central American and Caribbean Championships in Athletics
- Alfonso Rodriguez Jr. (born 1953), American sentenced to death penalty for murder
- Alfonso Rodríguez (director) Dominican actor, writer and director
- Alfonso Rodriguez (Captain), 17th-century Spanish mariner and merchant
- Alfonso Rodríguez (sport shooter), Colombian sport shooter