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{{short description| Denise Sheer is a Professor of Genetics with interests in Cancer and Genome Biology}}
{{short description|Professor of human genetics}}
{{Use dmy dates|date=September 2015}}
{{Use dmy dates|date=August 2020}}
{{Use South African English|date=September 2015}}
{{Use South African English|date=September 2015}}
{{Infobox scientist
{{Infobox scientist
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| caption =
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| birth_date =
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| birth_place = [[Johannesburg]], [[South Africa]]
| birth_place = [[Johannesburg]], [[South Africa]]
| death_date =
| death_date =
| death_place =
| death_place =
| residence = [[London]], [[United Kingdom]]
| citizenship =
| citizenship =
| nationality =
| nationality =
| ethnicity =
| ethnicity =
| field = [[Human Genetics]]
| field = [[Human Genetics]]
| work_institution = Institute of Cell and Molecular Science, [[Barts and The London, Queen Mary's School of Medicine and Dentistry]]
| work_institution = Institute of Cell and Molecular Science, [[Barts and The London, Queen Mary's School of Medicine and Dentistry]]
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| author_abbreviation_zoo =
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| prizes =
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| website =
| website = [http://www.researcherid.com/ProfileView.action?returnCode=ROUTER.Unauthorized&Init=Yes&SrcApp=CR&queryString=KG0UuZjN5Wlte3fin7unEwh2yAL11JR4gwX4PJtzynw%253D Denise Sheer]
| footnotes =
| footnotes =
}}
}}


'''Denise Sheer''' was appointed Professor of Human Genetics at The Institute of Cell and Molecular Science at [[Queen Mary, University of London]] in November 2006. Her fields of expertise include cell and molecular biology; cancer genetics and [[epigenetics]]; and molecular pathology of paediatric brain tumours.
'''Denise Sheer''' was appointed professor of human genetics at The Institute of Cell and Molecular Science at [[Queen Mary, University of London]] in November 2006. Her fields of expertise include cell and molecular biology; cancer genetics and [[epigenetics]]; and molecular pathology of paediatric brain tumours.


==Education and Career==
==Education and career==
Sheer completed a B.Sc (Hons) degree in [[Embryology]] and [[Zoology]] at the [[University of the Witwatersrand]], [[Johannesburg]] in 1973, after which she ran the diagnostic [[Cytogenetics]] laboratory at the [[National Health Laboratory Service|South African Institute of Medical Research]] for two years.{{R|ICMS}}
Sheer completed a BSc (Hons) degree in [[embryology]] and [[zoology]] at the [[University of the Witwatersrand]], [[Johannesburg]] in 1973, after which she ran the diagnostic [[cytogenetics]] laboratory at the [[National Health Laboratory Service|South African Institute of Medical Research]] for two years.{{R|ICMS}}


She then moved to the genetics laboratory of the [[University of Oxford]], where she was awarded a D.Phil in 1980. She completed a post-doctoral research fellowship at the [[Cancer Research UK|Imperial Cancer Research Fund (now the Cancer Research UK London Research Institute)]] and became head of the Human [[Cytogenetics]] Laboratory from 1983 to 2006. Here her work involved the identification of significant genetic aberrations in many [[malignant]] [[cancer]]s and she made critical discoveries on [[chromosome]] architecture.{{R|ICMS}}
She then moved to the genetics laboratory of the [[University of Oxford]], where she was awarded a D.Phil. in 1980. She completed a post-doctoral research fellowship at the [[Cancer Research UK|Imperial Cancer Research Fund (now the Cancer Research UK London Research Institute)]] and became head of the Human [[Cytogenetics]] Laboratory from 1983 to 2006. Here her work involved the identification of significant genetic aberrations in many [[malignant]] [[cancer]]s and she made critical discoveries on [[chromosome]] architecture.{{R|ICMS}}


In 2006 she moved with her research group to the Blizard Institute in the Centre for Genomics and Child Health at [[Barts and The London School of Medicine and Dentistry|Barts and The London, Queen Mary's School of Medicine and Dentistry]].{{R|Blizard}}
In 2006 she moved with her research group to the Blizard Institute in the Centre for Genomics and Child Health at [[Barts and The London School of Medicine and Dentistry|Barts and The London, Queen Mary's School of Medicine and Dentistry]].{{R|Blizard}}
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[[File:Glioma.gif|thumb|Glioma of the left parietal lobe. CT scan with contrast enhancement.]]
[[File:Glioma.gif|thumb|Glioma of the left parietal lobe. CT scan with contrast enhancement.]]


Sheer has 273 publications and 11,000 citations listed on [[ResearchGate]] and almost 15,000 citations listed on [[Google Scholar]]. The work done by Sheer and her group has been funded by the [[The Brain Tumour Charity]] since 2013{{R|YouTubeInt}} and she won the Research Engagement Award at [[The Brain Tumour Charity]] ''Celebrating You'' Awards{{R|YouTubeAward}}
Sheer has 273 publications and 11,000 citations listed on [[ResearchGate]] and almost 15,000 citations listed on [[Google Scholar]]. The work done by Sheer and her group has been funded by [[The Brain Tumour Charity]] since 2013{{R|YouTubeInt}} and she won the Research Engagement Award at [[The Brain Tumour Charity]] ''Celebrating You'' Awards{{R|YouTubeAward}}


==References==
==References==
{{reflist|refs=
{{reflist|refs=
⚫
<ref name="YouTubeAward">{{cite AV media| people = Professor Denise Sheer| date = 27 June 2018| title = The Research Engagement Award - Professor Denise Sheer - YouTube| medium = YouTube| url = https://www.youtube.com/watch?v=6U_C2fR4J20| access-date = 19 February 2019}}</ref>


<ref name="Astro">
⚫
<ref name="YouTubeInt">{{cite AV media| people = Professor Denise Sheer| date = March 2013| title = Professor Denise Sheer, March 2013 - YouTube| medium = YouTube| url = https://www.youtube.com/watch?v=jdJFvLRFCcw| access-date = 19 February 2019}}</ref>
⚫
{{cite web |title=AstroFund – Research |url=http://www.astrofund.org.uk/research.php |publisher=astrofund.org |accessdate=19 February 2019}}
</ref>


<ref name="AstroSheer">
⚫
<ref name="Astro">{{cite web |title=AstroFund - Research |url=http://www.astrofund.org.uk/research.php |publisher=astrofund.org |accessdate=19 February 2019}}</ref>
⚫
{{cite web |title=AstroFund – Sheer Research |url=http://www.astrofund.org.uk/sheerresearch.php |publisher=astrofund.org |accessdate=19 February 2019}}
</ref>


<ref name="Blizard">{{cite web |title=Sheer, Denise – Blizzard Institute |url=http://www.m.ibis-trials.org/staff/90-centre-for-genomics-and-child-health/378-sheer-denise.html |website=Blizzard Institute |publisher=Barts and The London School of Medicine and Dentistry |accessdate=19 February 2019 |archive-date=20 June 2019 |archive-url=https://web.archive.org/web/20190620180705/http://www.m.ibis-trials.org/staff/90-centre-for-genomics-and-child-health/378-sheer-denise.html |url-status=dead }}</ref>
⚫
<ref name="AstroSheer">{{cite web |title=AstroFund - Sheer Research |url=http://www.astrofund.org.uk/sheerresearch.php |publisher=astrofund.org |accessdate=19 February 2019}}</ref>


<ref name="ClinicalTrials">
<ref name="ICMS">{{cite web |title=Professor Denise Sheer B.Sc (Hons). D.Phil. |url=http://www.icms.qmul.ac.uk/Profiles/Neuroscience/Sheer%20Denise.htm |website=Institute of Cell and Molecular Science |publisher=Barts and The London, Queen Mary's School of Medicine and Dentistry |accessdate=19 February 2019 |archiveurl=https://web.archive.org/web/20090602223908/http://www.icms.qmul.ac.uk:80/Profiles/Neuroscience/Sheer%20Denise.htm |archivedate=2 June 2009 |location=The Wayback Machine}}</ref>
⚫
{{cite web |author1=National Cancer Institute |title=Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma |url=https://clinicaltrials.gov/ct2/show/NCT01089101 |website=ClinicalTrials.gov |publisher=US National Library of Medicine |accessdate=19 February 2019}}
</ref>


<ref name="Blizard">{{cite web |title=Sheer, Denise - Blizzard Institue |url=http://www.m.ibis-trials.org/staff/90-centre-for-genomics-and-child-health/378-sheer-denise.html |website=Blizzard Institute |publisher=Barts and The London School of Medicine and Dentistry |accessdate=19 February 2019}}</ref>
<ref name="ICMS">{{cite web |title=Professor Denise Sheer BSc (Hons). D.Phil. |url=http://www.icms.qmul.ac.uk/Profiles/Neuroscience/Sheer%20Denise.htm |website=Institute of Cell and Molecular Science |publisher=Barts and The London, Queen Mary's School of Medicine and Dentistry |accessdate=19 February 2019 |archiveurl=https://web.archive.org/web/20090602223908/http://www.icms.qmul.ac.uk/Profiles/Neuroscience/Sheer%20Denise.htm |archivedate=2 June 2009 |location=The Wayback Machine |url-status=dead }}</ref>


<ref name="YouTubeAward">
⚫
<ref name="ClinicalTrials">{{cite web |author1=National Cancer Institute |title=Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma |url=https://clinicaltrials.gov/ct2/show/NCT01089101 |website=ClinicalTrials.gov |publisher=US National Library of Medicine |accessdate=19 February 2019}}</ref>
⚫
{{cite AV media| people = The Brain Tumour Charity | date = 27 June 2018| title = The Research Engagement Award – Professor Denise Sheer – YouTube| medium = YouTube| url = https://www.youtube.com/watch?v=6U_C2fR4J20| access-date = 19 February 2019}}
</ref>

<ref name="YouTubeInt">
⚫
{{cite AV media| people = The Brain Tumour Charity| date = March 2013| title = Professor Denise Sheer, March 2013 – YouTube| medium = YouTube| url = https://www.youtube.com/watch?v=jdJFvLRFCcw| access-date = 19 February 2019}}
</ref>
}}
}}


==External Links==
==External links==
*{{google scholar id|P3SWTCMAAAAJ}}
*Denise Sheer on [https://scholar.google.com/citations?user=P3SWTCMAAAAJ Google Scholar]
*{{ResearchGate|Denise_Sheer}}
*Denise Sheer on [https://www.researchgate.net/profile/Denise_Sheer ResearchGate]
*Denise Sheer on [https://twitter.com/denisesheer Twitter]
*{{twitter|denisesheer}}
*[http://science.cancerresearchuk.org/research/loc/london/queen_marys_ms/asheerd Cancer Research UK website]
*[http://science.cancerresearchuk.org/research/loc/london/queen_marys_ms/asheerd Cancer Research UK website]


{{Authority control}}
{{Authority control}}



{{DEFAULTSORT:Sheer, Denise}}
{{DEFAULTSORT:Sheer, Denise}}
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[[Category:Living people]]
[[Category:Living people]]
[[Category:Alumni of the University of Oxford]]
[[Category:Alumni of the University of Oxford]]
[[Category:Academics of Queen Mary University of London]]
[[Category:Academics of Barts and The London School of Medicine and Dentistry]]
[[Category:South African geneticists]]
[[Category:South African geneticists]]
[[Category:University of the Witwatersrand alumni]]
[[Category:University of the Witwatersrand alumni]]

Latest revision as of 13:31, 26 January 2024

Denise Sheer
Born
Johannesburg, South Africa
Alma materUniversity of Oxford
Known forCancer Genetics, Genome Biology
Scientific career
FieldsHuman Genetics
InstitutionsInstitute of Cell and Molecular Science, Barts and The London, Queen Mary's School of Medicine and Dentistry

Denise Sheer was appointed professor of human genetics at The Institute of Cell and Molecular Science at Queen Mary, University of London in November 2006. Her fields of expertise include cell and molecular biology; cancer genetics and epigenetics; and molecular pathology of paediatric brain tumours.

Education and career[edit]

Sheer completed a BSc (Hons) degree in embryology and zoology at the University of the Witwatersrand, Johannesburg in 1973, after which she ran the diagnostic cytogenetics laboratory at the South African Institute of Medical Research for two years.[1]

She then moved to the genetics laboratory of the University of Oxford, where she was awarded a D.Phil. in 1980. She completed a post-doctoral research fellowship at the Imperial Cancer Research Fund (now the Cancer Research UK London Research Institute) and became head of the Human Cytogenetics Laboratory from 1983 to 2006. Here her work involved the identification of significant genetic aberrations in many malignant cancers and she made critical discoveries on chromosome architecture.[1]

In 2006 she moved with her research group to the Blizard Institute in the Centre for Genomics and Child Health at Barts and The London, Queen Mary's School of Medicine and Dentistry.[2]

The Blizard Building.

Her current research is an interventional clinical trial studying the treatment of young patients with recurrent or refractory low grade glioma, due for completion in 2020.[3][4] The group received the Jeremy Jass Prize for Excellence in Pathology for this work[5].

Glioma of the left parietal lobe. CT scan with contrast enhancement.

Sheer has 273 publications and 11,000 citations listed on ResearchGate and almost 15,000 citations listed on Google Scholar. The work done by Sheer and her group has been funded by The Brain Tumour Charity since 2013[6] and she won the Research Engagement Award at The Brain Tumour Charity Celebrating You Awards[7]

References[edit]

  1. ^ a b "Professor Denise Sheer BSc (Hons). D.Phil". Institute of Cell and Molecular Science. The Wayback Machine: Barts and The London, Queen Mary's School of Medicine and Dentistry. Archived from the original on 2 June 2009. Retrieved 19 February 2019.
  2. ^ "Sheer, Denise – Blizzard Institute". Blizzard Institute. Barts and The London School of Medicine and Dentistry. Archived from the original on 20 June 2019. Retrieved 19 February 2019.
  3. ^ National Cancer Institute. "Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma". ClinicalTrials.gov. US National Library of Medicine. Retrieved 19 February 2019.
  4. ^ "AstroFund – Sheer Research". astrofund.org. Retrieved 19 February 2019.
  5. ^ "AstroFund – Research". astrofund.org. Retrieved 19 February 2019.
  6. ^ The Brain Tumour Charity (March 2013). Professor Denise Sheer, March 2013 – YouTube (YouTube). Retrieved 19 February 2019.
  7. ^ The Brain Tumour Charity (27 June 2018). The Research Engagement Award – Professor Denise Sheer – YouTube (YouTube). Retrieved 19 February 2019.

External links[edit]

Retrieved from "https://en.wikipedia.org/w/index.php?title=Denise_Sheer&oldid=1199220652"