Radicicol: Difference between revisions
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'''Radicicol''', also known as '''monorden''', is a natural product that binds to [[Hsp90]] (Heat Shock Protein 90) and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, [[apoptosis]], [[angiogenesis]] and [[oncogenesis]]. |
'''Radicicol''', also known as '''monorden''', is a natural product that binds to [[Hsp90]] (Heat Shock Protein 90) and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, [[apoptosis]], [[angiogenesis]] and [[oncogenesis]]. |
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[http://www.rsc.org/Publishing/Journals/CC/article.asp?doi=b610344h Follow this link for a review cover the chemistry and biology of resorcylic acid lactones including radicicol] |
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==Further reading== |
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*{{cite journal |author=Winssinger N, Barluenga S |title=Chemistry and biology of resorcylic acid lactones |journal=Chem Commun |volume= |issue=1 |pages=22–36 |year=2007 |month=January |pmid=17279252 |doi=10.1039/b610344h}} Review of the chemistry and biology of resorcylic acid lactones, including radicicol. |
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Revision as of 22:33, 6 January 2009
Radicicol, also known as monorden, is a natural product that binds to Hsp90 (Heat Shock Protein 90) and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis.
Further reading
- Winssinger N, Barluenga S (2007). "Chemistry and biology of resorcylic acid lactones". Chem Commun (1): 22–36. doi:10.1039/b610344h. PMID 17279252.
{{cite journal}}: Unknown parameter|month=ignored (help) Review of the chemistry and biology of resorcylic acid lactones, including radicicol.
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