Sean Murphy
Sean Murphy may refer to:
- Sean Murphy (artist), American animator and comic book creator
- Sean Murphy (boxer), English Commonwealth Games Gold-winning boxer
- Sean Murphy (amateur boxer), Irish amateur boxer who won the 1996 Super Heavyweight Irish Elite Championship
- Sean Murphy (cryptographer), professor at Royal Holloway, University of London
- Seán Murphy (Gaelic footballer) (born 1932), retired Irish football player
- Sean Murphy (golfer) (born 1965), American professional golfer
- Sean Murphy (journalist) (born 1958), Australian journalist
- Sean Murphy (Oz), a fictional character on the television series Oz
- Sean Murphy (racing driver) (born 1984)
- Sean Murphy (swimmer) (born 1964), Canadian former backstroke swimmer
- Sean Murphy (baseball), baseball player
- Seán Murphy (hurler) (born 1947), Irish retired hurler
- Seán Óg Murphy (1897–1956), Irish hurler
- Sean D. Murphy (international lawyer), professor at George Washington University