Streptolydigin

Streptolydigin
Identifiers
	IUPAC name 2-[4-[6-(1,6-dimethylspiro[8,9-dioxabicyclo[3.3.1]non-3-ene-2,2'-oxirane]-7 -yl)-4-methylhepta-2,4-dienoyl]-5-hydroxy-1-(5-hydroxy-6-methyloxan-2-yl)-3 -oxo-2H-pyrrol-2-yl]-N-methylpropanamide;
CAS Number	7229-50-7;
PubChem CID	220508;
CompTox Dashboard (EPA)	DTXSID20905083 ;
Chemical and physical data
Formula	C32H44N2O9
Molar mass	600.708 g/mol g·mol−1

Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.

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