Non-Hodgkin lymphoma and Talk:List of minor planets: 96001–97000: Difference between pages

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The '''non-Hodgkin lymphomas''' are a diverse group of [[hematological malignancy|hematologic cancers]] which encompass any [[lymphoma]] other than [[Hodgkin lymphoma]].<ref>{{DorlandsDict|nine/000954456|non-Hodgkin lymphomas }}</ref> Lymphoma is a type of [[cancer]] derived from [[lymphocyte]]s, a type of [[white blood cell]]. Many subtypes of non-Hodgkin lymphoma have been described; these are generally grouped by their aggressiveness. Less aggressive non-Hodgkin lymphomas may be chronic diseases which exist for many years, while more aggressive non-Hodgkin lymphomas can be rapidly fatal without treatment. Non-Hodgkin lymphomas are treated with combinations of [[chemotherapy]], [[monoclonal antibody|monoclonal antibodies]], [[immunotherapy]], [[radiation therapy|radiation]], and [[hematopoietic stem cell transplantation]].

==History==
[[Hodgkin's Lymphoma]] (HL, Hodgkin's disease), described by [[Thomas Hodgkin]] in [[1832]], was the first form of lymphoma described and defined. Other forms were later described and there was a need to classify them. Because Hodgkin's lymphoma was much more radiation-sensitive than other forms, its diagnosis was important for oncologists and their patients. Thus, research originally focused on it. The first classification of Hodgkin's Lymphoma was proposed by [[Robert J. Lukes]] in 1963.

While consensus was rapidly reached on the classification of Hodgkin's lymphoma, there remained a large group of very different diseases requiring further classification. The Rappaport classification, proposed by [[Henry Rappaport]] in 1956 and 1966, became the first widely accepted classification of lymphomas other than Hodgkin's. Following its publication in 1982, the [[Working Formulation]] became the standard classification for this group of diseases. It introduced the term '''Non-Hodgkin's Lymphoma''' (NHL) and defined three [[grade]]s of lymphoma.

However, NHL consists of 16 different conditions that have little in common with each other. Without further narrowing, the label is of limited usefulness for patients or doctors. The most recent lymphoma classifications, the 1994 Revised European-American Lymphoma (REAL) classification and the 2001 [[World Health Organization|WHO]] classification, abandoned the HL vs. NHL grouping. Instead, 43 different forms of lymphoma are listed and discussed separately.

==Modern usage of term==
Nevertheless, the Working formulation and the NHL category continue to be used by many. To this day, lymphoma statistics are compiled as Hodgkin's vs Non-Hodgkin's lymphoma by major cancer agencies, including the [[National Cancer Institute]] in its [[Editing Surveillance, Epidemiology, and End Results (SEER)|SEER]] program, the [[Canadian Cancer Society]] and the [[International Agency for Research on Cancer|IARC]].

==See also==
* [[Lymphoma]], for information about all forms of NHL as well as Hodgkin's lymphoma
*[http://lymphomas.org.uk Lymphoma Association provides accurate medical information and support to lymphatic cancer patients, their families, friends and carers]

==References==
{{reflist}}

{{Hematology}}
{{Hematological malignancy histology}}

[[Category:Blood disorders]]
[[Category:Types of cancer]]

[[de:Non-Hodgkin-Lymphom]]
[[es:Linfoma no-Hodgkin]]
[[fr:Lymphome non-hodgkinien]]
[[it:Linfoma non Hodgkin]]
[[nl:Non-Hodgkinlymfoom]]
[[ja:非ホジキンリンパ腫]]
[[pl:Chłoniaki nieziarnicze]]
[[pt:Linfoma não-Hodgkin]]
[[fi:Non-Hodgkinin lymfooma]]
[[sv:Non-Hodgkins lymfom]]
[[tr:Hodgkin dışı lenfoma]]

Revision as of 22:03, 3 October 2008