Aganglionosis

As aganglionosis an innate is lack of nerve cells in the intestinal wall called, usually in the rectum and / or colon . The result is a permanent contraction in the transition zone to the normal intestine with disturbance of intestinal mobility ( peristalsis ), a stool and a massive expansion of the intestine in front of it, so-called megacolon .

Intramural ganglion cells of the submucosal plexus and myenteric plexus ( in the wall of the rectum and the sigmoid colon , less often of the entire colon) are affected .

For clinical symptoms, diagnostics and treatment options, see the clinical pictures

• Hirschsprung's disease , congenital megacolon
• Zuelzer-Wilson syndrome , entire colon affected

Individual evidence

1. ^ W. Pschyrembel: Clinical dictionary. 265th edition. Verlag Walter de Gruyter, Berlin 2014, ISBN 978-3-11-018534-8 .
2. ↑ M. Bettex, N. Genton, M. Stockmann (Ed.): Pediatric surgery. Diagnostics, indication, therapy, prognosis. 2nd Edition. Thieme, Stuttgart 1982, ISBN 3-13-338102-4 .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !