Basic rest activity cycle
The Basic Rest-Activity Cycle (BRAC) of the brain , which is present in both sleep and wake phases, is a hypothesis put forward by Nathaniel Kleitman .
After the discovery and description of REM sleep in 1953 by Eugene Aserinsky and Nathaniel Kleitman, the hypothesis was based on the later observation of the rhythmic alternation between NREM and REM sleep and implemented the findings and considerations made in the process.
In 1982, Kleitman referred to a large number of studies which had been carried out since the hypothesis was drawn up and which gave reasonable cause for the assumption of a continuous rest-activity cycle in the range 80–120 minutes. Nevertheless, the state of research on the hypothesis to this day gives an inconsistent picture.
Individual evidence
- ^ Nathaniel Kleitman : Sleep and Wakefulness. Revised and enlarged edition. University of Chicago Press, Chicago IL et al. 1963 (Revised and enlarged edition, reprint. Ibid 1987, ISBN 0-226-44073-7 ).
- ^ Nathaniel Kleitman: Basic rest-activity cycle - 22 years later. In: Sleep. Volume 5, Number 4, 1982, ISSN 0161-8105 , pp. 311-317, PMID 6819628 , online PDF ( Memento from March 5, 2016 in the Internet Archive ).