Besinger score
The Besinger score is a clinical score for assessing the severity of myasthenia gravis . It was first presented in an article by Besinger and co-workers in 1983 and later modified. The Besinger score is used to assess clinical progress. It is made up of eight easy-to-collect criteria.
| Normal (0) | Light (1) | Medium (2) | Hard (3) | |
|---|---|---|---|---|
| Hold up arms attempt (90 degrees, standing or sitting) | > 180 s | 61-180 s | 11-60 s | 0-10 s |
| Leg hold attempt (45 degrees, supine position) | > 45 s | 31-45 s | 6–30 s | 0-5 s |
| Head hold attempt (45 degrees, lying) | > 90 s | 31-90 s | 6–30 s | 0-5 s |
| Vital capacity (women) | > 3.0 L | 2.1-3.0 L. | 1.2-2.0 L. | <1.2 L |
| Vital capacity (men) | > 4.0 L | 2.6-4.0 L. | 1.5-2.5 L. | <1.5 L |
| Chewing , swallowing | normal | Easily disturbed with solid meals | Disturbed only with liquids, partial regurgitation | Not possible (gastric tube) |
| Mimic muscles (eyelid closure) | Normally strong eyelid closure | Slight weakness when the eyelid closes completely | Incomplete lid closure | No facial expression |
| Double vision (look to the side) | > 60 s | 11-60 s | 1-10 s | spontaneous |
| Ptosis (looking up) | > 60 s | 11-60 s | 1-10 s | spontaneous |
The result is calculated from the sum of the points divided by the number of criteria tested.
example
| attempt | Duration | score |
|---|---|---|
| Hold up arm | 20 s | 2 points |
| Hold your leg up | 6 s | 2 points |
| Lift head | 7 s | 2 points |
| Double vision | spontaneous | 3 points |
| Ptosis when looking up | 50 s | 1 point |
| Sum : | 10 points |
Reduced myasthenia score: 10: 5 = 2.0 points
A change of 0.5 points is assessed as significant over time.
Individual evidence
- ↑ UA Besinger, KV Toyka u. a .: Myasthenia gravis: long-term correlation of binding and bungarotoxin blocking antibodies against acetylcholine receptors with changes in disease severity. In: Neurology. Volume 33, Number 10, October 1983, pp. 1316-1321, PMID 6684226 .
- ↑ A. Jaretzki, RJ Barohn et al. a .: Myasthenia gravis: recommendations for clinical research standards. Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America. In: Neurology. Vol. 55, Number 1, July 2000, pp. 16-23, PMID 10891897 (review).