Bland-White-Garland Syndrome

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Classification according to ICD-10
Q24.5 Coronary artery malformation

Abnormal origin of the coronary artery from the pulmonary artery

ICD-10 online (WHO version 2019)

The anomalous left coronary artery from the pulmonary artery (in the international language also Anomalous Left Coronary Artery From the Pulmonary Artery , ALCAPA) refers to a congenital origin of the left coronary artery (main trunk) from the pulmonary artery , its incidence from 0.25 to 0.5% of all congenital heart defects . People with this malformation often develop myocardial ischemia and cardiac insufficiency at a young age . Due to the pressure conditions, the flow direction of the blood takes place from the right coronary artery via collaterals into the left coronary artery and via this into the pulmonary artery. Depending on the characteristics of the collaterals, a distinction is made between an infantile type and an adult type . The only curative therapy is surgical correction.

The syndrome is named after the American cardiologists Edward Franklin Bland (1901–1992), Joseph Garland (1893–1973) and Paul Dudley White (1886–1973).

Individual evidence

  1. Reinhard Larsen: Anesthesia and intensive medicine in cardiac, thoracic and vascular surgery. (1st edition 1986) 5th edition. Springer, Berlin / Heidelberg / New York et al. 1999, ISBN 3-540-65024-5 , pp. 386-388.
  2. Micha Maeder et al .: Bland-White-Garland Syndrome in a 39-Year-Old Mother? In: Ann Thorac Surg . (2004); 78, pp. 1451-1453.