Brushfield spots
Brushfield spots ( German : Brushfield Patch ), also Brushfield spots written and the synonym Brushfield iris mottling known, by an accumulation of Stromafasern resulting ophthalmic tissue changes / pigment peculiarities in the front layers of the iris (iris) of the eye .
They can be recognized particularly well in the case of a light iris as ring-shaped white, light yellow or light gray speckles ( spots ) on the outside of the iris.
The special iris speckle was described for the first time from a scientific point of view in 1924 by Thomas Brushfield .
Brushfield spots occur more often than average in childhood in people with Down syndrome ( trisomy 21 ), Smith-Magenis syndrome or Zellweger syndrome .
They disappear with age, do not affect vision and therefore do not require treatment.