Calcinosis
| Classification according to ICD-10 | |
|---|---|
| E83.5 | Disorders of calcium metabolism |
| ICD-10 online (WHO version 2019) | |
Calcinosis (lat .: calcinosis ) means abundance of lime and is the name for the pathological deposition of calcium salts (as amorphous hydroxyapatite , calcium phosphate or calcium pyrophosphate and small amounts of calcium carbonate ) in the skin and in body organs.
to form
Calcinosis cutis is a calcinosis of the skin. The categorization of sub-forms is not uniform, especially in English-speaking and German-speaking areas. The subforms include:
- Calcinosis metastatica is a form of calcinosis cutis in which the calcium phosphate metabolism is disturbed (see hypercalcemia ). Deposits are also possible in the internal organs, e.g. B. kidney, stomach or lungs.
- Depending on the occurrence of calcium salts, Calcinosis metabolica is divided into Calcinosis circumscripta (also: Calcinosis localisata ) with individual small nodules in the skin and joints and Calcinosis universalis (also: Calcinosis generalisata or Calcinosis diffusa ) with numerous deposits in the skin, subcutaneous tissue and differentiated from other organs. The calcinosis universalis is also called Lipokalzinogranulomatose referred.
- Calcinosis dystrophica are calcium deposits without any detectable disturbance of the calcium metabolism and can accompany several diseases such as tumors , varices , phlebolites , tubercular lymphomas and local trauma .
- Idiopathic calcinosis is a form in which neither metabolic disorders nor other external influences are detected, usually an area is affected
- Iatrogenic calcinosis as a result of treatment
Calcinosis intervertebralis are calcium deposits in the intervertebral discs , mostly as a result of rheumatic processes or ochronosis .
A benign, very rare calcinosis of unknown cause is tumorous calcinosis ( Teutschländer's disease ), in which calcified tumors slowly grow in the soft tissues in the immediate vicinity of the large joints. The cause is mutations in the genes for GALNT3 , FGF23 or KLOTHO . This mainly affects black Africans up to the age of 20.
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- Tumorous calcinosis, case report with pictures - Quiz Page October 2008: Pain in the Buttock in a Dialysis Patient . In: American Journal of Kidney Diseases . Vol. 52, Issue 4, 2008, pp. A45-A46 ( article ).
