Disease X

Disease X ( German , disease X ') referred to in the future possibly occurring infectious diseases, can be taken for which no specific provision because it is not yet known how those unknown to pathogens will behave and look like the diseases they cause. This placeholder name was defined by the World Health Organization (WHO).

The purpose of the wildcard is to identify the potential for a new epidemic / pandemic caused by an unknown pathogen in order to prepare for it in advance through research and development .

In January 2020 in the first English-language news media began, the coronavirus outbreak 2019-20 as Disease X to call.

The WHO definition is:

“Disease X represents the understanding that a serious international epidemic could be caused by a pathogen that is currently not known to cause disease in humans. This is why the R&D concept explicitly tries to enable comprehensive R&D preparation as far as possible, which is also relevant for a previously unknown "disease X". "

The Coalition for Epidemic Preparedness Innovations (CEPI) supports the development of vaccination platforms that enable the rapid provision of vaccines against previously unknown diseases (Disease X).

Web links

Prioritization of diseases for research and development in emergency contexts

Individual evidence

↑ BT-Drs. 19/19275
↑ Peter Daszak : We Knew Disease X Was Coming. It's Here Now. In: The New York Times . February 27, 2020, ISSN 0362-4331 ( nytimes.com [accessed March 1, 2020]).
^ Coronavirus: "Disease X", the unknown next disease . In: The time . February 29, 2020, ISSN 0044-2070 ( zeit.de [accessed on March 1, 2020]): “Some researchers claim that: They want to research" Disease X ", the next unknown disease. There are also laboratories where viruses or bacteria are mutated just so that a therapy can then be developed. But when you look at how complicated it is just to predict the next week for the new coronavirus, it becomes clear how difficult it is to say anything about "Disease X". "
↑ ^a ^b Prioritizing diseases for research and development in emergency contexts. Retrieved March 1, 2020 .
↑ What is Disease X? February 26, 2020, accessed March 1, 2020 (American English).
↑ Bruce Y. Lee: Disease X Is What May Become The Biggest Infectious Threat To Our World. Retrieved March 1, 2020 .
↑ Tom Fish: Disease X: 'SARS-like' virus spreading through China prompts alert - 'Really concerning' ( en ) January 18, 2020. Retrieved January 18, 2020.
^ Anne Gulland: Have Chinese researchers uncovered the new disease X? (en-GB) . In: The Telegraph , January 9, 2020. Retrieved January 18, 2020.
^ Priority diseases. In: cepi.net. May 30, 2019, accessed March 15, 2020 .
^ R. Hatchett, N. Lurie: Outbreak response as an essential component of vaccine development. In: The Lancet. Infectious diseases. Volume 19, number 11, November 2019, pp. E399 – e403, doi : 10.1016 / S1473-3099 (19) 30305-6 , PMID 31256955 (review).
↑ B. Huneycutt, N. Lurie et al. a .: Finding equipoise: CEPI revises its equitable access policy. In: Vaccine . Volume 38, number 9, February 2020, pp. 2144-2148, doi : 10.1016 / j.vaccine.2019.12.055 , PMID 32005536 (review).

[1] BT-Drs. 19/19275

[2] Peter Daszak : We Knew Disease X Was Coming. It's Here Now. In: The New York Times . February 27, 2020, ISSN 0362-4331 ( nytimes.com [accessed March 1, 2020]).

[3] Coronavirus: "Disease X", the unknown next disease . In: The time . February 29, 2020, ISSN 0044-2070 ( zeit.de [accessed on March 1, 2020]): “Some researchers claim that: They want to research" Disease X ", the next unknown disease. There are also laboratories where viruses or bacteria are mutated just so that a therapy can then be developed. But when you look at how complicated it is just to predict the next week for the new coronavirus, it becomes clear how difficult it is to say anything about "Disease X". "

[:0-4] Prioritizing diseases for research and development in emergency contexts. Retrieved March 1, 2020 .

[5] What is Disease X? February 26, 2020, accessed March 1, 2020 (American English).

[6] Bruce Y. Lee: Disease X Is What May Become The Biggest Infectious Threat To Our World. Retrieved March 1, 2020 .

[7] Tom Fish: Disease X: 'SARS-like' virus spreading through China prompts alert - 'Really concerning' ( en ) January 18, 2020. Retrieved January 18, 2020.

[8] Anne Gulland: Have Chinese researchers uncovered the new disease X? (en-GB) . In: The Telegraph , January 9, 2020. Retrieved January 18, 2020.

[cepi-Priority-9] Priority diseases. In: cepi.net. May 30, 2019, accessed March 15, 2020 .

[PMID31256955-10] R. Hatchett, N. Lurie: Outbreak response as an essential component of vaccine development. In: The Lancet. Infectious diseases. Volume 19, number 11, November 2019, pp. E399 – e403, doi : 10.1016 / S1473-3099 (19) 30305-6 , PMID 31256955 (review).

[PMID32005536-11] B. Huneycutt, N. Lurie et al. a .: Finding equipoise: CEPI revises its equitable access policy. In: Vaccine . Volume 38, number 9, February 2020, pp. 2144-2148, doi : 10.1016 / j.vaccine.2019.12.055 , PMID 32005536 (review).