Disfacilitation

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Disfacilitation (syn. Inhibition, alleviation reduction) describes in neurophysiology the process of suppressing a tonic excitation of a nerve cell .

Animal experiments have shown that after hyperpolarization of cortical nerve cells lasting longer than 200 ms, the inhibitory postsynaptic potential is also followed by disfacilitation. It is postulated that the inhibition of inter neurons is responsible.

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  1. ^ Col F .: The Basal Ganglia, 2004; last viewed on January 31, 2008 ( memento of January 27, 2004 in the Internet Archive ).
  2. a b Vieth J. ea .: Evoked disinhibition and reduction in facilitation in cortical nerve cells, European Archives of Psychiatry and Clinical Neuroscience, 5/06; last viewed on January 31, 2008 .