Embolia cutis medicamentosa

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Classification according to ICD-10
T80.1 Vascular complications following infusion, transfusion, or injection for therapeutic purposes
ICD-10 online (WHO version 2019)

Under embolia cutis medicamentosa (synonym: Nicolau syndrome , also livedo-left dermatitis ) refers to a so-called drug syndrome as a result of intramuscular injection may occur.

The cause is an accidental injection of a mostly crystalloid substance into an artery . This leads to an embolism in the affected blood vessel and, as a result, to a reduced blood supply ( ischemia ) to the skin in the area of ​​the injection site. Because of this long-term undersupply, the affected area dies locally ( necrosis ).

Individual evidence

  1. Lorenzo Ceroni, Klaus Garbe, Dieter Metze, Heinz Kutzner Helmut Kerl (eds.): Histopathologie der Haut , 2nd edition, Springer Verlag, Berlin 2003, ISBN 978-3-66245132-8 , page 226
  2. Entry on Embolia cutis medicamentosa in Altenkämper's Encyclopedia (online) Springer Verlag 2017