Francis Willoughby
Francis Willoughby is the name of the following people:
- Francis Willoughby, 5th Baron Willoughby of Parham (1605–1666), British colonizer of Suriname
- Francis Willoughby (1635–1672), British naturalist, see Francis Willughby
- Francis Willoughby, 1st Baronet (1668–1688), British nobleman
- Francis Willoughby, 2nd Baron Middleton (1692–1758), British nobleman
- Francis Willoughby, 3rd Baron Middleton (1726–1774), British nobleman