Frits Rosendaal

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Frits Rosendaal (2002)

Frits Richard Rosendaal (born October 5, 1959 in Rotterdam ) is a Dutch physician and epidemiologist with a special focus on thrombosis and hemophilia .

Rosendaal studied medicine at the Erasmus University Rotterdam and graduated in 1985. In 1989 he received his doctorate from the University of Leiden with a thesis on hemophilia. Since then he has been working at this university, since 1997 as Professor of Clinical Epidemiology. He has been Head of Clinical Epidemiology in Leiden since 1999 and the Thrombosis and Hemostasis Department since 2007 .

In his dissertation ( Hemophilia: the best of times, the worst of times ) he dealt with medical and social aspects of the treatment of hemophilia, especially with regard to AIDS . He directed the Leiden Thrombophilia Study (LETS), which identified various risk factors for venous thrombosis (such as Factor V Leiden, Prothrombin 20210A, high levels of Factor VIII, IX, XI and TAFI). His research also found that women with the abnormal Factor V Leiden gene were seven times more likely to develop thrombosis than the average of women, that 3rd generation birth control pills led to a higher susceptibility to thrombosis (especially with Leiden Factor V, with a ten-fold increase higher risk of thrombosis than other women taking birth control pills). He was involved in the European EPCOT study on genetic causes of thrombosis, the WRIGHT study (relationship between air travel and thrombosis), the MEGA study (influence of genes and the environment on thrombosis), all on venous thrombosis. He was also involved in studies on the coagulation system and risk of myocardial infarction (SMILE) and birth control pills and abnormalities in the coagulation system and infarction, stroke and arterial disease in young women (RATIO) and in the Dutch study on the epidemiology of obesity (NEO).

In 2002 he received the Spinoza Prize in particular for the elucidation of (genetic) risk factors for thrombosis. He is board member of the Dutch Society for Thrombosis and Haeemostasis (NVTH) and board member of the Council of the International Society on Thrombosis and Haeemostasis (ISTH), member of the National Health Council of the Netherlands and member of the Royal Netherlands Academy of Sciences. He is co-editor of the Journal of Thrombosis and Haemostasis .

Fonts

  • with C. Smit, E. Briet: Hemophilia treatment in historical perspective. A review of medical and social devopments . In: Annals of Hematology . Volume 62, 1991, p. 5

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