Guillermo Rodríguez
Guillermo Rodríguez is the name of the following people:
- Guillermo Rodríguez (soccer player) (* 1984), Uruguayan soccer player
- Guillermo Rodríguez (musician) (1923–2020), Ecuadorian requinto player and composer
- Guillermo Rodríguez Lara (* 1924), Ecuadorian military and politician, President 1972 to 1976
- Guillermo Rodríguez-Melgarejo (* 1943), Argentine clergyman, Bishop of San Martín