Skin blister test

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The skin blister test (or blister test , cantharidin test ) is an experimental method for investigating the distribution of a substance ( active ingredient or drug ) in the interstitial fluid . In pharmacokinetics, it is used to determine the ability of a substance to penetrate tissue when it is applied to the skin or its concentration in the interstitium .

When blister test, a highly irritating substance (usually cantharidin ) of the skin applied, thereby resulting in a liquid-filled blister (engl. Blister forms). For example, the concentration of an administered drug in the liquid (an exudate ) can be determined.

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